This review focuses on the current knowledge of the effects of thyroid hormones on central
nervous system differentiation and development in animals and the human fetal brain. The …

The current review focuses on the molecular mechanisms and developmental roles of
thyroid hormone receptors (TRs) in gene regulation and metamorphosis in Xenopus laevis …

Life history theory seeks to explain the evolution of the major features of life cycles by
analyzing the ecological factors that shape age-specific schedules of growth, reproduction …

Publisher Summary Amphibians exhibit considerable diversity in behavioral, physiological,
and life history strategies. They are geographically widespread, occupying a diverse range …

In multicellular organisms, development is based in part on the integration of communication
systems. Two neuroendocrine axes, the hypothalamic–pituitary–thyroid and the …

Thyroid hormone induces the complete metamorphosis of anuran tadpoles into juvenile
frogs. Arguably, anuran metamorphosis is the most dramatic effect of a hormone in any …

Concern over global amphibian declines and possible links to agrochemical use has led to
research on the endocrine disrupting actions of agrochemicals, such as fertilizers …

During amphibian metamorphosis, the larval tissues/organs rapidly degenerate to adapt
from the aquatic to the terrestrial life. At the cellular level, a large quantity of apoptosis occurs …

Thyroid hormone (TH) is the most important hormone in frog metamorphosis, a
developmental process which will not occur in the absence of TH but can be induced …

Thyroid hormone (T3) affects adult metabolism and postembryonic development in
vertebrates. T3 functions mainly via binding to its receptors (TRs) to regulate gene …