F Perera, J Herbstman - Reproductive toxicology, 2011 - Elsevier
This review summarizes recent evidence that prenatal exposure to diverse environmental chemicals dysregulates the fetal epigenome, with potential consequences for subsequent …
AB Rodgers, CP Morgan, SL Bronson… - Journal of …, 2013 - Soc Neuroscience
Neuropsychiatric disease frequently presents with an underlying hyporeactivity or hyperreactivity of the HPA stress axis, suggesting an exceptional vulnerability of this circuitry …
In utero exposure to environmental stress in both animals and humans could result in long- term epigenome alterations which further lead to consequences for adaptation and …
J Borgel, S Guibert, Y Li, H Chiba, D Schübeler… - Nature …, 2010 - nature.com
DNA methylation is extensively reprogrammed during the early phases of mammalian development, yet genomic targets of this process are largely unknown. We optimized …
TM Hardy, TO Tollefsbol - Epigenomics, 2011 - Taylor & Francis
A number of bioactive dietary components are of particular interest in the field of epigenetics. Many of these compounds display anticancer properties and may play a role in cancer …
EA Mazzio, KFA Soliman - Epigenetics, 2012 - Taylor & Francis
Through epigenetic modifications, specific long-term phenotypic consequences can arise from environmental influence on slowly evolving genomic DNA. Heritable epigenetic …
A Janesick, B Blumberg - Birth Defects Research Part C …, 2011 - Wiley Online Library
Obesity and related disorders are a burgeoning public health epidemic, particularly in the US Currently 34% of the US population is clinically obese (BMI> 30) and 68% are …
Environmental epigenetics has an important role in regulating phenotype formation or disease etiology. The ability of environmental factors and exposures early in life to alter …
X Yan, MJ Zhu, MV Dodson, M Du - Journal of genomics, 2013 - ncbi.nlm.nih.gov
All important developmental milestones are accomplished during the fetal stage, and nutrient fluctuation during this stage produces lasting effects on offspring health, so called …