Epigenetics and lifestyle

JA Alegría-Torres, A Baccarelli, V Bollati - Epigenomics, 2011 - Taylor & Francis
The concept of 'lifestyle 'includes different factors such as nutrition, behavior, stress, physical
activity, working habits, smoking and alcohol consumption. Increasing evidence shows that …

Prenatal environmental exposures, epigenetics, and disease

F Perera, J Herbstman - Reproductive toxicology, 2011 - Elsevier
This review summarizes recent evidence that prenatal exposure to diverse environmental
chemicals dysregulates the fetal epigenome, with potential consequences for subsequent …

Paternal stress exposure alters sperm microRNA content and reprograms offspring HPA stress axis regulation

AB Rodgers, CP Morgan, SL Bronson… - Journal of …, 2013 - Soc Neuroscience
Neuropsychiatric disease frequently presents with an underlying hyporeactivity or
hyperreactivity of the HPA stress axis, suggesting an exceptional vulnerability of this circuitry …

Prenatal stress and epigenetics

L Cao-Lei, SR De Rooij, S King, SG Matthews… - Neuroscience & …, 2020 - Elsevier
In utero exposure to environmental stress in both animals and humans could result in long-
term epigenome alterations which further lead to consequences for adaptation and …

Targets and dynamics of promoter DNA methylation during early mouse development

J Borgel, S Guibert, Y Li, H Chiba, D Schübeler… - Nature …, 2010 - nature.com
DNA methylation is extensively reprogrammed during the early phases of mammalian
development, yet genomic targets of this process are largely unknown. We optimized …

Epigenetic diet: impact on the epigenome and cancer

TM Hardy, TO Tollefsbol - Epigenomics, 2011 - Taylor & Francis
A number of bioactive dietary components are of particular interest in the field of epigenetics.
Many of these compounds display anticancer properties and may play a role in cancer …

Basic concepts of epigenetics: impact of environmental signals on gene expression

EA Mazzio, KFA Soliman - Epigenetics, 2012 - Taylor & Francis
Through epigenetic modifications, specific long-term phenotypic consequences can arise
from environmental influence on slowly evolving genomic DNA. Heritable epigenetic …

Endocrine disrupting chemicals and the developmental programming of adipogenesis and obesity

A Janesick, B Blumberg - Birth Defects Research Part C …, 2011 - Wiley Online Library
Obesity and related disorders are a burgeoning public health epidemic, particularly in the
US Currently 34% of the US population is clinically obese (BMI> 30) and 68% are …

Environmentally induced epigenetic transgenerational inheritance of phenotype and disease

C Guerrero-Bosagna, MK Skinner - Molecular and cellular endocrinology, 2012 - Elsevier
Environmental epigenetics has an important role in regulating phenotype formation or
disease etiology. The ability of environmental factors and exposures early in life to alter …

[HTML][HTML] Developmental programming of fetal skeletal muscle and adipose tissue development

X Yan, MJ Zhu, MV Dodson, M Du - Journal of genomics, 2013 - ncbi.nlm.nih.gov
All important developmental milestones are accomplished during the fetal stage, and
nutrient fluctuation during this stage produces lasting effects on offspring health, so called …