Strategies and opportunities of micro/nano delivery systems for targeted therapy of ulcerative colitis: Focus on underlying mechanisms and future perspectives

Z Liu, H Liu, J Cheng, H Wang, Y Yang, J Ye… - Chinese Chemical …, 2024 - Elsevier
Ulcerative colitis (UC) is a common progressive inflammatory disease whose incidence has
increased rapidly in recent years, and can develop into colorectal cancer in severe cases …

Orally-administered nanomedicine systems targeting colon inflammation for the treatment of inflammatory bowel disease: latest advances

S Hu, R Zhao, Y Xu, Z Gu, B Zhu, J Hu - Journal of Materials Chemistry …, 2024 - pubs.rsc.org
Inflammatory bowel disease (IBD) is a chronic and idiopathic condition that results in
inflammation of the gastrointestinal tract, leading to conditions such as ulcerative colitis and …

[HTML][HTML] Dual pH and microbial-sensitive galactosylated polymeric nanocargoes for multi-level targeting to combat ulcerative colitis

M Zeeshan, QU Ain, B Weigmann, D Story… - Asian Journal of …, 2023 - Elsevier
Ulcerative colitis (UC) is a type of inflammatory bowel disease characterized by
inflammation, ulcers and irritation of the mucosal lining. Oral drug delivery in UC encounters …

pH-Sensitive Tacrolimus loaded nanostructured lipid carriers for the treatment of inflammatory bowel disease

S Altaf, M Zeeshan, H Ali, A Zeb, I Afzal, A Imran… - European Journal of …, 2024 - Elsevier
Abstract Inflammatory Bowel Disease is the chronic tissue inflammation of the lower part of
the Gastrointestinal tract (GIT). Conventional therapeutic approaches face numerous …

QbD‐Based Fabrication of Biomimetic Hydroxyapatite Embedded Gelatin Nanoparticles for Localized Drug Delivery against Deteriorated Arthritic Joint Architecture

QU Ain, M Zeeshan, D Mazhar, A Zeb… - Macromolecular …, 2024 - Wiley Online Library
Biomaterials such as nanohydroxyapatite and gelatin are widely explored to improve
damaged joint architecture associated with rheumatoid arthritis (RA). Besides joint damage …

Biomaterials for inflammatory bowel disease: treatment, diagnosis and organoids

J Wang, Y Shi, B Mao, B Zhang, J Yang, Z Hu… - Applied Materials …, 2024 - Elsevier
Inflammatory bowel disease (IBD) is a chronic gastrointestinal disease characterized by
intestinal tract inflammation. Although the incidence of IBD is increasing globally, the …

A Review on Nanosystem-Based Delivery of Tofacitinib for Enhanced Treatment of Autoimmune Diseases and Inflammation

TTL Nguyen, VA Duong - BioNanoScience, 2024 - Springer
Tofacitinib is the first Janus kinase inhibitor approved by the United States Food and Drug
Administration to manage rheumatoid arthritis, psoriatic arthritis, ulcerative colitis, and …