Animal models of pulmonary arterial hypertension: the hope for etiological discovery and pharmacological cure

KR Stenmark, B Meyrick, N Galie… - … of Physiology-Lung …, 2009 - journals.physiology.org
At present, six groups of chronic pulmonary hypertension (PH) are described. Among these,
group 1 (and 1′) comprises a group of diverse diseases termed pulmonary arterial …

Cardiovascular risk reduction in high-risk pediatric patients: a scientific statement from the American Heart Association expert panel on population and prevention …

REW Kavey, V Allada, SR Daniels, LL Hayman… - Circulation, 2006 - Am Heart Assoc
Although for most children the process of atherosclerosis is subclinical, dramatically
accelerated atherosclerosis occurs in some pediatric disease states, with clinical coronary …

[HTML][HTML] Kawasaki disease: an update on diagnosis and treatment

HC Kuo, KD Yang, WC Chang, LP Ger… - Pediatrics & Neonatology, 2012 - Elsevier
Kawasaki disease (KD) is an acute multi-system vasculitis syndrome of unknown etiology
occurring mostly in infants and children younger than 5 years of age. In developed countries …

The arterial reservoir pressure increases with aging and is the major determinant of the aortic augmentation index

JE Davies, J Baksi, DP Francis… - American Journal …, 2010 - journals.physiology.org
The augmentation index predicts cardiovascular mortality and is usually explained as a
distally reflected wave adding to the forward wave generated by systole. We propose that …

A meta-analysis of the mechanism of blood pressure change with aging

AJ Baksi, TA Treibel, JE Davies, N Hadjiloizou… - Journal of the American …, 2009 - jacc.org
Objectives: We undertook a meta-analysis to determine whether changes in wave reflection
substantiate the consensus explanation of why blood pressure (BP) changes with aging …

Long-term outcome of Kawasaki disease

H Senzaki - Circulation, 2008 - Am Heart Assoc
Kawasaki disease was first reported in 1967 by Japanese pediatrician Tomisaku Kawasaki
as an acute febrile syndrome mainly affecting the skin, mucosa, and lymph nodes. 1 …

Kawasaki disease: late cardiovascular sequelae

LB Daniels, JB Gordon, JC Burns - Current opinion in cardiology, 2012 - journals.lww.com
The vasculopathy of Kawasaki disease appears to be distinct from that of atherosclerosis,
and optimal management strategies for the two conditions differ. Patients with persistent or …

Relationship between carotid intima-media thickness and arterial stiffness in children after Kawasaki disease

YF Cheung, SJ Wong, MHK Ho - Archives of Disease In Childhood, 2007 - adc.bmj.com
Background: Evidence of premature atherosclerosis and systemic arterial stiffening in
patients after Kawasaki disease is accumulating. Aim: To test the hypothesis that carotid …

The pathophysiology of coronary artery aneurysms in Kawasaki disease: role of matrix metalloproteinases

H Senzaki - Archives of disease in childhood, 2006 - adc.bmj.com
Kawasaki disease is an acute inflammatory syndrome that takes the form of systemic
vasculitis, and predominantly affects children. Important complications of this disease are …

Arterial haemodynamics in patients after repair of tetralogy of Fallot: influence on left ventricular after load and aortic dilatation

H Senzaki, Y Iwamoto, H Ishido, T Matsunaga… - Heart, 2008 - heart.bmj.com
Background: Recent histological studies of the aortic wall of patients with tetralogy of Fallot
(TOF) have shown massive degeneration of the tunica media of the aorta. Such changes in …