Mechanism of action of ribosomally synthesized and post-translationally modified peptides

C Ongpipattanakul, EK Desormeaux… - Chemical …, 2022 - ACS Publications
Ribosomally synthesized and post-translationally modified peptides (RiPPs) are a natural
product class that has undergone significant expansion due to the rapid growth in genome …

Antimicrobial peptides: an update on classifications and databases

A Bin Hafeez, X Jiang, PJ Bergen, Y Zhu - International journal of …, 2021 - mdpi.com
Antimicrobial peptides (AMPs) are distributed across all kingdoms of life and are an
indispensable component of host defenses. They consist of predominantly short cationic …

Small molecules from the human microbiota

MS Donia, MA Fischbach - Science, 2015 - science.org
BACKGROUND Two developments in distinct fields are converging to create interest in
discovering small molecules from the human microbiome. First, the use of genomics to guide …

Oral commensal streptococci: gatekeepers of the oral cavity

JJ Baty, SN Stoner, JA Scoffield - Journal of Bacteriology, 2022 - Am Soc Microbiol
Oral commensal streptococci are primary colonizers of the oral cavity. These streptococci
produce many adhesins, metabolites, and antimicrobials that modulate microbial succession …

Mobilization of microbiota commensals and their bacteriocins for therapeutics

P Hols, L Ledesma-García, P Gabant, J Mignolet - Trends in microbiology, 2019 - cell.com
With the specter of resurgence of pathogens due to the propagation of antibiotic-resistance
genes, innovative antimicrobial strategies are needed. In this review, we summarize the …

[HTML][HTML] Antibacterial activity, cytotoxicity, and the mechanism of action of bacteriocin from Bacillus subtilis GAS101

G Sharma, S Dang, S Gupta, R Gabrani - Medical Principles and …, 2018 - karger.com
Objective: The aim of this study was to purify and characterize bacteriocin from the soil
isolate Bacillus subtilis GAS101, and to determine its antimicrobial as well as antibiofilm …

Purification and Characterization of Bacteriocin Produced by Weissella confusa A3 of Dairy Origin

HF Goh, K Philip - PloS one, 2015 - journals.plos.org
A dramatic increase in bacterial resistance towards currently available antibiotics has raised
worldwide concerns for public health. Therefore, antimicrobial peptides (AMPs) have …

Purification, characterization and mode of action of plantaricin K25 produced by Lactobacillus plantarum

LS Wen, K Philip, N Ajam - Food control, 2016 - Elsevier
The aim of this study was to elucidate the mode of action of a novel bacteriocin with low
molecular weight that was isolated, purified and characterised from Lactobacillus plantarum …

Evolution of lantibiotic salivaricins: new weapons to fight infectious diseases

A Barbour, P Wescombe, L Smith - Trends in microbiology, 2020 - cell.com
Lantibiotic salivaricins are polycyclic peptides containing lanthionine and/or β-
methyllanthionine residues produced by certain strains of Streptococcus salivarius, which …

In silico analysis of bacteriocins from lactic acid bacteria against SARS-CoV-2

I Erol, SE Kotil, O Fidan, AE Yetiman, S Durdagi… - Probiotics and …, 2023 - Springer
The COVID-19 pandemic caused by a novel coronavirus (SARS-CoV-2) is a serious health
concern in the twenty-first century for scientists, health workers, and all humans. The …