Extracellular vesicles, inflammation, and cardiovascular disease

A Akhmerov, T Parimon - Cells, 2022 - mdpi.com
Cardiovascular disease is a leading cause of death worldwide. The underlying mechanisms
of most cardiovascular disorders involve innate and adaptive immune responses, and …

Regulatory T cells and cardiovascular diseases

W Hu, J Li, X Cheng - Chinese Medical Journal, 2023 - mednexus.org
Inflammation is a major underlying mechanism in the progression of numerous
cardiovascular diseases (CVDs). Regulatory T cells (Tregs) are typical immune regulatory …

[HTML][HTML] Harnessing the potential of mesenchymal stem cells–derived exosomes in degenerative diseases

HJ Liao, YP Yang, YH Liu, HC Tseng, TI Huo… - Regenerative …, 2024 - Elsevier
Mesenchymal stem cells (MSCs) have gained attention as a promising therapeutic approach
in both preclinical and clinical osteoarthritis (OA) settings. Various joint cell types, such as …

Targeting regulatory T cells for cardiovascular diseases

X Wang, H Zhou, Q Liu, P Cheng, T Zhao… - Frontiers in …, 2023 - frontiersin.org
Cardiovascular diseases (CVDs) are the leading cause of death and disability worldwide.
The CVDs are accompanied by inflammatory progression, resulting in innate and adaptive …

[HTML][HTML] Cellular Immunology of Myocarditis: Lights and Shades—A Literature Review

C Vicenzetto, AS Giordani, C Menghi, A Baritussio… - Cells, 2024 - mdpi.com
Myocarditis is an inflammatory disease of the myocardium with heterogeneous etiology,
clinical presentation, and prognosis; when it is associated with myocardial dysfunction, this …

The ALPHA phase 1 study: pulmonary ArteriaL hypertension treated with CardiosPHere-Derived allogeneic stem cells

MI Lewis, S Shapiro, RJ Oudiz, M Nakamura, D Geft… - Ebiomedicine, 2024 - thelancet.com
Summary Background Pulmonary Arterial Hypertension (PAH) is a progressive condition
with no cure. Even with pharmacologic advances, survival remains poor. Lung pathology on …

Urine-derived stem cells: Promising advancements and applications in regenerative medicine and beyond

Y Sun, H Zhao, S Yang, G Wang, L Zhu, C Sun, Y An - Heliyon, 2024 - cell.com
Currently, stem cells are a prominent focus of regenerative engineering research. However,
due to the limitations of commonly used stem cell sources, their application in therapy is …

Role of immune cells in the pathogenesis of myocarditis

K Liu, B Han - Journal of Leukocyte Biology, 2024 - academic.oup.com
Myocarditis is an inflammatory heart disease that mostly affects young people. Myocarditis
involves a complex immune network; however, its detailed pathogenesis is currently …

[HTML][HTML] Extracellular Vesicle-Derived Non-Coding RNAs: Key Mediators in Remodelling Heart Failure

J Zhao, H Huang - Current Issues in Molecular Biology, 2024 - mdpi.com
Heart failure (HF), a syndrome of persistent development of cardiac insufficiency due to
various heart diseases, is a serious and lethal disease for which specific curative therapies …

[HTML][HTML] Assessment of mechanisms of infectious pneumonia based on expression of fibrinogen, procalcitonin, high-sensitivity C-reactive protein expression, T helper …

DM Zu, L Zhang - Translational Pediatrics, 2022 - ncbi.nlm.nih.gov
Background Infectious pneumonia is one of the important causes of neonatal death that can
lead to the imbalance of T helper 17 cells (Th17) and T regulatory T cells (Treg) cells. The …