Recent strategies to develop innovative photosensitizers for enhanced photodynamic therapy
TC Pham, VN Nguyen, Y Choi, S Lee, J Yoon - Chemical reviews, 2021 - ACS Publications
This review presents a robust strategy to design photosensitizers (PSs) for various species.
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …
Recent progress in photosensitizers for overcoming the challenges of photodynamic therapy: from molecular design to application
Photodynamic therapy (PDT), a therapeutic mode involving light triggering, has been
recognized as an attractive oncotherapy treatment. However, nonnegligible challenges …
recognized as an attractive oncotherapy treatment. However, nonnegligible challenges …
Cyclic ruthenium-peptide conjugates as integrin-targeting phototherapeutic prodrugs for the treatment of brain tumors
To investigate the potential of tumor-targeting photoactivated chemotherapy, a chiral
ruthenium-based anticancer warhead, Λ/Δ-[Ru (Ph2phen) 2 (OH2) 2] 2+, was conjugated to …
ruthenium-based anticancer warhead, Λ/Δ-[Ru (Ph2phen) 2 (OH2) 2] 2+, was conjugated to …
Recent advances in functional nanomaterials for light–triggered cancer therapy
Photo–triggered therapeutic modalities for cancer have attracted enormous attention in
recent years due to the easily focused and tuned properties of irradiation light that enable …
recent years due to the easily focused and tuned properties of irradiation light that enable …
The development of ruthenium (II) polypyridyl complexes and conjugates for in vitro cellular and in vivo applications
Ruthenium (II)[Ru (II)] polypyridyl complexes have been the focus of intense investigations
since work began exploring their supramolecular interactions with DNA. In recent years …
since work began exploring their supramolecular interactions with DNA. In recent years …
[HTML][HTML] Polymer bioconjugates: Modern design concepts toward precision hybrid materials
The conjugation of synthetic polymers with various biomolecules provides an easy access to
biohybrid materials which combine advantages from both the synthetic world and Nature …
biohybrid materials which combine advantages from both the synthetic world and Nature …
Mitochondria targeted protein-ruthenium photosensitizer for efficient photodynamic applications
S Chakrabortty, BK Agrawalla, A Stumper… - Journal of the …, 2017 - ACS Publications
Organelle-targeted photosensitization represents a promising approach in photodynamic
therapy where the design of the active photosensitizer (PS) is very crucial. In this work, we …
therapy where the design of the active photosensitizer (PS) is very crucial. In this work, we …
Harnessing ruthenium (II) as photodynamic agents: Encouraging advances in cancer therapy
Despite their past triumphs, platinum-based therapeutics remain limited by chemo-
resistance and severe side effects. As an alternative therapeutic modality which bypasses …
resistance and severe side effects. As an alternative therapeutic modality which bypasses …
Transition metal complexes as photosensitizers for integrated cancer theranostic applications
J Li, T Chen - Coordination Chemistry Reviews, 2020 - Elsevier
Light, oxygen and photosensitizers (PSs) are the three separate elements that have been
applied in combination in the phototherapy of cancers in the past decades. Currently …
applied in combination in the phototherapy of cancers in the past decades. Currently …
Chemical technology principles for selective bioconjugation of proteins and antibodies
Proteins are multifunctional large organic compounds that constitute an essential
component of a living system. Hence, control over their bioconjugation impacts science at …
component of a living system. Hence, control over their bioconjugation impacts science at …