CRISPR technology: A decade of genome editing is only the beginning
JY Wang, JA Doudna - Science, 2023 - science.org
The advent of clustered regularly interspaced short palindromic repeat (CRISPR) genome
editing, coupled with advances in computing and imaging capabilities, has initiated a new …
editing, coupled with advances in computing and imaging capabilities, has initiated a new …
Applications of CRISPR–Cas in agriculture and plant biotechnology
The prokaryote-derived CRISPR–Cas genome editing technology has altered plant
molecular biology beyond all expectations. Characterized by robustness and high target …
molecular biology beyond all expectations. Characterized by robustness and high target …
Latest developed strategies to minimize the off-target effects in CRISPR-Cas-mediated genome editing
Gene editing that makes target gene modification in the genome by deletion or addition has
revolutionized the era of biomedicine. Clustered regularly interspaced short palindromic …
revolutionized the era of biomedicine. Clustered regularly interspaced short palindromic …
CRISPR/Cas genome editing and precision plant breeding in agriculture
K Chen, Y Wang, R Zhang, H Zhang… - Annual review of plant …, 2019 - annualreviews.org
Enhanced agricultural production through innovative breeding technology is urgently
needed to increase access to nutritious foods worldwide. Recent advances in CRISPR/Cas …
needed to increase access to nutritious foods worldwide. Recent advances in CRISPR/Cas …
CRISPR for crop improvement: an update review
The availability of genome sequences for several crops and advances in genome editing
approaches has opened up possibilities to breed for almost any given desirable trait …
approaches has opened up possibilities to breed for almost any given desirable trait …
The emerging and uncultivated potential of CRISPR technology in plant science
The application of clustered regularly interspaced short palindromic repeats (CRISPR) for
genetic manipulation has revolutionized life science over the past few years. CRISPR was …
genetic manipulation has revolutionized life science over the past few years. CRISPR was …
Designing future crops: challenges and strategies for sustainable agriculture
Z Tian, JW Wang, J Li, B Han - The Plant Journal, 2021 - Wiley Online Library
Crop production is facing unprecedented challenges. Despite the fact that the food supply
has significantly increased over the past half‐century,~ 8.9 and 14.3% people are still …
has significantly increased over the past half‐century,~ 8.9 and 14.3% people are still …
Applications and potential of genome editing in crop improvement
Genome-editing tools provide advanced biotechnological techniques that enable the
precise and efficient targeted modification of an organism's genome. Genome-editing …
precise and efficient targeted modification of an organism's genome. Genome-editing …
Boosting plant genome editing with a versatile CRISPR-Combo system
CRISPR-Cas9, its derived base editors and CRISPR activation systems have greatly aided
genome engineering in plants. However, these systems are mostly used separately, leaving …
genome engineering in plants. However, these systems are mostly used separately, leaving …
CRISPR–Act3. 0 for highly efficient multiplexed gene activation in plants
RNA-guided CRISPR activation (CRISPRa) systems have been developed in plants.
However, the simultaneous activation of multiple genes remains challenging. Here, we …
However, the simultaneous activation of multiple genes remains challenging. Here, we …