An evidence-based approach to psychopharmacology for posttraumatic stress disorder (PTSD)-2022 update

LA Bajor, C Balsara, DN Osser - Psychiatry research, 2022 - Elsevier
Algorithms for posttraumatic stress disorder were published by this team in 1999 and 2011.
Developments since then warrant revision. New studies and review articles from January …

A proposed mechanism for the MDMA-mediated extinction of traumatic memories in PTSD patients treated with MDMA-assisted therapy

RJ Sottile, T Vida - Frontiers in psychiatry, 2022 - frontiersin.org
Post-traumatic stress disorder (PTSD) is a devastating psychiatric disorder afflicting millions
of people around the world. Characterized by severe anxiety, intrusive thoughts, pervasive …

[HTML][HTML] At-home, sublingual ketamine telehealth is a safe and effective treatment for moderate to severe anxiety and depression: findings from a large, prospective …

TD Hull, M Malgaroli, A Gazzaley, TJ Akiki… - Journal of Affective …, 2022 - Elsevier
Abstract Background At-home Ketamine-assisted therapy (KAT) with psychosocial support
and remote monitoring through telehealth platforms addresses access barriers, including the …

Dose-related effects of ketamine for antidepressant-resistant symptoms of posttraumatic stress disorder in veterans and active duty military: a double-blind …

CG Abdallah, JD Roache, R Gueorguieva… - …, 2022 - nature.com
This study tested the efficacy of repeated intravenous ketamine doses to reduce symptoms
of posttraumatic stress disorder (PTSD). Veterans and service members with PTSD (n= 158) …

Psychopharmaka

MJ Lohse, J Seifert, S Bleich - Arzneiverordnungs-Report 2021, 2021 - Springer
Zusammenfassung Auf einen Blick Zusammenfassung Mit weit über 2 Milliarden DDD
stellen die Psychopharmaka eine der größten Arzneimittelgruppen dar. Dabei sind die seit …

Acute ketamine facilitates fear memory extinction in a rat model of PTSD along with restoring glutamatergic alterations and dendritic atrophy in the prefrontal cortex

N Sala, C Paoli, T Bonifacino, J Mingardi… - Frontiers in …, 2022 - frontiersin.org
Stress represents a major risk factor for psychiatric disorders, including post-traumatic stress
disorder (PTSD). Recently, we dissected the destabilizing effects of acute stress on the …

Cannabinoids as therapeutics for PTSD

B Sbarski, I Akirav - Pharmacology & therapeutics, 2020 - Elsevier
Post-traumatic stress disorder (PTSD) is a complex disorder that involves dysregulation of
multiple neurobiological systems. The traumatic stressor plays a causal role in producing …

Depression in post-traumatic stress disorder

ML Radell, EA Hamza, AA Moustafa - Reviews in the Neurosciences, 2020 - degruyter.com
Major depressive disorder (MDD) symptoms commonly occur after trauma-exposure, both
alone and in combination with post-traumatic stress disorder (PTSD). This article reviews …

MDMA-based psychotherapy in treatment-resistant post-traumatic stress disorder (PTSD): a brief narrative overview of current evidence

K Riaz, S Suneel, M Hamza Bin Abdul Malik, T Kashif… - Diseases, 2023 - mdpi.com
Post-traumatic stress disorder (PTSD) is a debilitating mental health disorder that causes
significant dysfunction in individuals. Currently, there are many approved pharmacotherapy …

The Psychopharmacology Algorithm Project at the Harvard South Shore Program: an update on posttraumatic stress disorder

LA Bajor, AN Ticlea, DN Osser - Harvard review of psychiatry, 2011 - journals.lww.com
Background: This project aimed to provide an organized, sequential, and evidence-
supported approach to the pharmacotherapy of posttraumatic stress disorder (PTSD) …