CMH Singleton, S Brar, N Robertson, L DiTommaso… - Plos one, 2023 - journals.plos.org
Background Cardiometabolic risk factors (impaired fasting glucose, abdominal obesity, high blood pressure, dyslipidemia) cluster in children, may predict adult disease burden, and are …
JP Bradfield, S Vogelezang, JF Felix… - Human molecular …, 2019 - academic.oup.com
Although hundreds of genome-wide association studies-implicated loci have been reported for adult obesity-related traits, less is known about the genetics specific for early-onset …
In the developing brain, cell-surface proteins play crucial roles, but their protein-protein interaction network remains largely unknown. A proteomic screen identified 200 interactions …
Obesity and overweight are worldwide public health problems with an evident genetic predisposition that is still poorly understood. In addition, great variability has been described …
ACP da Fonseca, GM Abreu… - … and Obesity: Targets …, 2019 - Taylor & Francis
Background: Obesity occurs due to the interaction between the genetic background and environmental factors, including an increased food intake and a sedentary lifestyle …
J Kang, RC Guan, Y Zhao, Y Chen - BMC Medical Genetics, 2020 - Springer
Background Several obesity susceptibility loci in genes, including GNPDA2, SH2B1, TMEM18, MTCH2, CDKAL1, FAIM2, and MC4R, have been identified by genome-wide …
PF Todendi, EI Klinger, ACR Geraldo… - British Journal of …, 2019 - cambridge.org
The prevalence of childhood obesity has increased worldwide. Although it is considered a polygenic inheritance disease, little is known about its susceptibility when the additive effect …
The scarcity of the results obtained for the treatment of obesity leads us to consider new strategies, contemplating all the factors involved in the development of the disease. One of …
Background Many genetic polymorphisms identified by genome‐wide association studies for adult body mass index (BMI) have been suggested to regulate food intake. Objective The …