Impact of the obesity epidemic on cancer

PJ Goodwin, V Stambolic - Annual review of medicine, 2015 - annualreviews.org
There is growing appreciation that the current obesity epidemic is associated with increases
in cancer incidence at a population level and may lead to poor cancer outcomes; concurrent …

Therapeutic approaches targeting molecular signaling pathways common to diabetes, lung diseases and cancer

R Raguraman, A Srivastava, A Munshi… - Advanced drug delivery …, 2021 - Elsevier
Diabetes mellitus (DM), is the most common metabolic disease and is characterized by
sustained hyperglycemia. Accumulating evidences supports a strong association between …

[HTML][HTML] A pilot study evaluating steroid-induced diabetes after antiemetic dexamethasone therapy in chemotherapy-treated cancer patients

Y Jeong, HS Han, HD Lee, J Yang… - … : official journal of …, 2016 - synapse.koreamed.org
Purpose Dexamethasone is a mainstay antiemetic regimen for the prevention of
chemotherapy-induced nausea and vomiting. The aim of this pilot study was to assess the …

Impact of glycemia on survival of glioblastoma patients treated with radiation and temozolomide

MT Tieu, LE Lovblom, MG McNamara, W Mason… - Journal of neuro …, 2015 - Springer
Evidence suggests hyperglycemia is associated with worse outcomes in glioblastoma (GB).
This study aims to confirm the association between glycemia during radiotherapy (RT) and …

Targeting the Warburg Effect in Cancer: Where Do We Stand?

I Barba, L Carrillo-Bosch, J Seoane - International Journal of Molecular …, 2024 - mdpi.com
The Warburg effect, characterized by the preferential conversion of glucose to lactate even
in the presence of oxygen and functional mitochondria, is a prominent metabolic hallmark of …

Serum and whole blood Cu and Zn status in predicting mortality in lung cancer patients

K Zabłocka-Słowińska, A Prescha, S Płaczkowska… - Nutrients, 2020 - mdpi.com
Alterations in circulating Cu and Zn are negative predictors of survival in neoplastic patients
and are known during lung cancer. However, no data on predicting mortality of lung cancer …

[HTML][HTML] High glucose promotes tumor invasion and increases metastasis-associated protein expression in human lung epithelial cells by upregulating heme …

X Kang, F Kong, X Wu, Y Ren, S Wu, K Wu… - Cellular Physiology and …, 2015 - karger.com
Background: Growing evidence indicates that heme oxygenase-1 (HO-1) is up-regulated in
malignancies and subsequently alters tumor aggressiveness and various cancer-related …

Metabolism changes caused by glucose in normal and cancer human brain cell lines by Raman imaging and chemometric methods

M Kopec, K Beton-Mysur, J Surmacki, H Abramczyk - Scientific Reports, 2024 - nature.com
Glucose is the main source of energy for the human brain. This paper presents a non-
invasive technique to study metabolic changes caused by glucose in human brain cell lines …

The effect of diabetes mellitus on lung cancer prognosis: a PRISMA-compliant meta-analysis of cohort studies

L Zhu, H Cao, T Zhang, H Shen, W Dong, L Wang… - Medicine, 2016 - journals.lww.com
Previous studies suggested that diabetes mellitus (DM) was associated with risk and
mortality of cancer, but studies investigating the correlation between DM and lung cancer …

Expression of insulin-like growth factor 1 receptor (IGF-1R) predicts poor responses to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors in non-small …

CD Yeo, KH Park, CK Park, SH Lee, SJ Kim, HK Yoon… - Lung cancer, 2015 - Elsevier
Objectives Expression of insulin-like growth factor 1 receptor (IGF-1R) in non-small cell lung
cancer (NSCLC) is associated with poor prognosis. The IGF-1R pathway activates …