Risk Prediction in Diverticulitis

J Velez-Padilla, JP Del Valle… - Clinics in Colon and …, 2024 - thieme-connect.com
Acute diverticulitis is a common sequela of colonic diverticulosis that often poses a
significant dilemma for surgeons and patients considering surgical management of the …

The Patient Perspective on Colectomy for Recurrent Diverticulitis: A Qualitative Study

AT Hawkins, DF Penson, TM Geiger, KR Bonnet… - Annals of …, 2024 - journals.lww.com
Objective: Understand the patient's decision-making process regarding colectomy for
recurrent diverticulitis. Background: The decision to pursue elective colectomy for recurrent …

Current Management of Diverticulitis

R Garfinkle, M Boutros - Advances in Surgery, 2024 - advancessurgery.com
INTRODUCTION Sigmoid diverticulitis remains one of the greatest health care burdens
facing general and colorectal surgeons across North America. In the United States alone …

Diverticulitis familiality: a statewide case-control study

JN Cohan, JJ Horns, JM Ramsay… - Journal of the …, 2023 - journals.lww.com
BACKGROUND: The etiology of diverticulitis is multifactorial and poorly understood. We
estimated the familiality of diverticulitis using the Utah Population Database, a statewide …

Multiancestry transferability of a polygenic risk score for diverticulitis

TE Ueland, JD Mosley, C Neylan… - BMJ Open …, 2024 - bmjopengastro.bmj.com
Objective Polygenic risk scores (PRS) for diverticular disease must be evaluated in diverse
cohorts. We sought to explore shared genetic predisposition across the phenome and to …

Development of a Polygenic Risk Score to Predict Diverticulitis

HD Schaeffer, DT Smelser, HS Rao… - Diseases of the Colon …, 2024 - journals.lww.com
BACKGROUND: Despite its prevalence and associated morbidity, we remain limited in our
ability to predict the course of a patient with diverticular disease. Although several clinical …

Research Protocol: Discrete choice modelling to understand the influence of sharing polygenic risk scores related to cardiovascular disease risk with primary care …

L Bowker-Lonnecker, P Dixon, S Petrou, J Buckell - medRxiv, 2024 - medrxiv.org
Introduction Cardiovascular disease (CVD) is a leading cause of death in the UK and
globally. People identified as being at high risk may receive further investigations or …

Genetics-Based Multi-Omics Analysis Identify Novel Candidate Biomarkers Associated with Heel Bone Mineral Density

X Yang, H Liu, K Xu, D He, S Cheng, C Pan, L Liu… - papers.ssrn.com
Objectives: Bone mineral density (BMD) is an indirect detection tool for osteoporosis (OP).
Utilizing the latest multi-omics quantitative trait loci (QTLs) data, we aimed to identify novel …

Study Populations and Phenotyping

TE Ueland - bmjopengastro.bmj.com
Clinical information for BioVU participants is maintained in a deidentified database of
Vanderbilt University Medical Center's electronic medical record, the Synthetic Derivative …