The biologically relevant coordination chemistry of iron and nitric oxide: electronic structure and reactivity

N Lehnert, E Kim, HT Dong, JB Harland… - Chemical …, 2021 - ACS Publications
Nitric oxide (NO) is an important signaling molecule that is involved in a wide range of
physiological and pathological events in biology. Metal coordination chemistry, especially …

Bioanalytical applications of Mössbauer spectroscopy

AA Kamnev, AV Tugarova - Russian Chemical Reviews, 2021 - iopscience.iop.org
Data on the applications of Mössbauer spectroscopy in the transmission (mainly on 57 Fe
nuclei) and emission (on 57 Co nuclei) variants for analytical studies at the molecular level …

Distortion of the [FeNO]2 Core in Flavodiiron Nitric Oxide Reductase Models Inhibits N–N Bond Formation and Promotes Formation of Unusual Dinitrosyl Iron …

CJ White, MO Lengel, AJ Bracken… - Journal of the …, 2022 - ACS Publications
Flavodiiron nitric oxide reductases (FNORs) carry out the reduction of nitric oxide (NO) to
nitrous oxide (N2O), allowing infectious pathogens to mitigate toxic levels of NO generated …

What Is the Right Level of Activation of a High-Spin {FeNO}7 Complex to Enable Direct N–N Coupling? Mechanistic Insight into Flavodiiron NO Reductases

HT Dong, S Camarena, D Sil, MO Lengel… - Journal of the …, 2022 - ACS Publications
Flavodiiron nitric oxide reductases (FNORs), found in pathogenic bacteria, are capable of
reducing nitric oxide (NO) to nitrous oxide (N2O) to detoxify NO released by the human …

Nitrite Formation at a Diiron Dinitrosyl Complex

AL Poptic, JK Klinger, SL Carter… - Journal of the …, 2023 - ACS Publications
Pathogenic bacteria employ iron-containing enzymes to detoxify nitric oxide (NO•) produced
by mammals as part of their immune response. Two classes of diiron proteins, flavodiiron …

The Effect of Intramolecular Proton Transfer on the Mechanism of NO Reduction to N2O by a Copper Complex: A DFT Study

R Toyoshima, Y Kametani, K Yoshizawa… - Inorganic …, 2024 - ACS Publications
DFT calculations were performed to explore the mechanism underlying the reduction of NO
to N2O by a CuI complex. A nitrosyl complex reacts with another NO molecule and the CuI …

Bacterial nitric oxide reductase (NorBC) models employing click chemistry

JB Harland, S Samanta, N Lehnert - Journal of Inorganic Biochemistry, 2023 - Elsevier
Abstract Bacterial NO Reductase (NorBC or cNOR) is a membrane-bound enzyme found in
denitrifying bacteria that catalyzes the two-electron reduction of NO to N 2 O and water. The …

Reductive Coupling of Nitric Oxide by Cu(I): Stepwise Formation of Mono- and Dinitrosyl Species En Route to a Cupric Hyponitrite Intermediate

M Bhadra, T Albert, A Franke, V Josef… - Journal of the …, 2023 - ACS Publications
Transition-metal-mediated reductive coupling of nitric oxide (NO (g)) to nitrous oxide (N2O
(g)) has significance across the fields of industrial chemistry, biochemistry, medicine, and …

Activation of non-heme iron-nitrosyl complexes: Turning up the heat

N Lehnert, K Fujisawa, S Camarena, HT Dong… - ACS …, 2019 - ACS Publications
The chemistry of nonheme iron centers with NO in different oxidation states has experienced
a renaissance in the last 10 years because of recent findings of their involvement in N2O …

Stable salts of heteroleptic iron carbonyl/nitrosyl cations

J Bohnenberger, I Krossing - … Chemie International Edition, 2020 - Wiley Online Library
The oxidation of Fe (CO) 5 with the [NO]+ salt of the weakly coordinating
perfluoroalkoxyaluminate anion [F‐{Al (ORF) 3} 2]−(RF= C (CF3) 3) leads to stable salts of …