Signaling pathways involved in diabetic renal fibrosis

Y Zhang, D Jin, X Kang, R Zhou, Y Sun… - Frontiers in cell and …, 2021 - frontiersin.org
Diabetic kidney disease (DKD), as the most common complication of diabetes mellitus (DM),
is the major cause of end-stage renal disease (ESRD). Renal interstitial fibrosis is a crucial …

[HTML][HTML] Trends and perspectives for improving quality of chronic kidney disease care: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) …

KU Eckardt, C Delgado, HJL Heerspink… - Kidney international, 2023 - Elsevier
Chronic kidney disease (CKD) affects over 850 million people globally, and there is an
urgent need to prevent its development and progression. During the last decade, new …

Probing renal microstructure and function with advanced diffusion MRI: concepts, applications, challenges, and future directions

J Stabinska, HJ Wittsack, LO Lerman… - Journal of Magnetic …, 2024 - Wiley Online Library
Diffusion measurements in the kidney are affected not only by renal microstructure but also
by physiological processes (ie, glomerular filtration, water reabsorption, and urine …

From inflammation to renal fibrosis: A one-way road in autoimmunity?

D Roccatello, HY Lan, S Sciascia, S Sethi… - Autoimmunity …, 2024 - Elsevier
Renal fibrosis is now recognized as a main determinant of renal pathology to include
chronic kidney disease. Deposition of pathological matrix in the walls of glomerular …

Ginkgo biloba extract attenuates cisplatin-induced renal interstitial fibrosis by inhibiting the activation of renal fibroblasts through down-regulating the HIF-1α/STAT3/IL …

Y Zhang, X Qin, Y Yang, J Li, X Li, X Zou, Z Huang… - Phytomedicine, 2023 - Elsevier
Background Activation of renal fibroblasts into myofibroblasts plays an important role in
promoting renal interstitial fibrosis (RIF). Ginkgo biloba extract (EGb) can alleviate RIF …

Effectiveness of functional magnetic resonance imaging for early identification of chronic kidney disease: a systematic review and network meta-analysis

H Zhou, Y Si, J Sun, J Deng, L Yang, Y Tang… - European Journal of …, 2023 - Elsevier
Purpose The commonly used clinical indicators are not sensitive enough on detecting early
chronic kidney disease (CKD), whether functional magnetic resonance imaging (fMRI) can …

Diffusion-weighted, intravoxel incoherent motion, and diffusion kurtosis tensor MR imaging in chronic kidney diseases: correlations with histology

J Zhu, A Chen, J Gao, M Zou, J Du, PY Wu… - Magnetic Resonance …, 2024 - Elsevier
Objectives To probe the correlations of parameters derived from standard DWI and its
extending models including intravoxel incoherent motion (IVIM), diffusion tensor imaging …

Noninvasive diagnosis of interstitial fibrosis in chronic kidney disease: a systematic review and meta-analysis

S Wan, S Wang, X He, C Song, J Wang - Renal failure, 2024 - Taylor & Francis
Rationale and objectives Researchers have delved into noninvasive diagnostic methods of
renal fibrosis (RF) in chronic kidney disease, including ultrasound (US), magnetic resonance …

Arterial spin labeling and diffusion-weighted MR imaging: quantitative assessment of renal pathological injury in chronic kidney disease

S Pi, Y Li, C Lin, G Li, H Wen, H Peng, J Wang - Abdominal Radiology, 2023 - Springer
Purpose The aim of the study was to investigate the performance of arterial spin labeling
(ASL), diffusion-weighted imaging (DWI), and clinical biomarkers in assessing renal …

The clinical and pathological evaluation of patients with immunoglobulin A nephropathy by diffusion tensor imaging and intravoxel incoherent motion diffusion …

H Zhou, Y Si, L Yang, Y Wang, Y Xiao… - British Journal of …, 2024 - academic.oup.com
Objectives To explore the efficacy of diffuse magnetic resonance imaging (MRI) for
identifying clinicopathological changes in immunoglobulin A nephropathy (IgAN) patients …