Ocular diseases seriously affect patients' vision and life quality, with a global morbidity of
over 43 million blindness. However, efficient drug delivery to treat ocular diseases …

Albumin, a multifunctional protein, is widely used to prepare nanocarriers. Hyaluronic acid
(HA) is a natural glycosaminoglycan that can specifically bind receptors, such as cluster of …

The lack of efficient therapeutic options for many severe disorders including cancer spurs
demand for improved drug delivery technologies. Nanoscale drug delivery systems based …

Effective drug delivery to the retina still remains a challenge due to ocular elimination
mechanisms and complex barriers that selectively limit the entry of drugs into the eye. To …

Posterior segment diseases, such as age-related macular degeneration (AMD) and diabetic
retinopathy (DR) are vital factor that seriously threatens human vision health and quality of …

Nanoparticles have been widely prepared during the past decades. In fact, encapsulation
could provide several advantages over conventional pharmaceutical forms (Miladi et al. in …

Objectives We aim to quantify the effect of size and degree of folate loading of folate-
decorated polymeric nanoparticles (NPs) on the kinetics of cellular uptake and the selection …

Ocular drug delivery remains the focus of much modern research. Primary routes of
administration include the surface, the intravitreal space, the subretinal space, and the …

Posterior segment eye disease is a leading cause of irreversible vision impairment and
blindness. As the unique organ for vision, eyes are protected by various protective barriers …

The complex network of neuronal cells in the retina makes it a potential target of neuronal
toxicity–a risk factor for visual loss. With growing use of nanoparticles (NPs) in commercial …