Sustained release glaucoma therapies: Novel modalities for overcoming key treatment barriers associated with topical medications

A Belamkar, A Harris, R Zukerman, B Siesky… - Annals of …, 2022 - Taylor & Francis
Glaucoma is a progressive optic neuropathy and a leading cause of irreversible blindness.
The disease has conventionally been characterized by an elevated intraocular pressure …

Exogenous influences on intraocular pressure

YW Kim, KH Park - British Journal of Ophthalmology, 2019 - bjo.bmj.com
Intraocular pressure (IOP), the pressure within the eyeball, is a function mainly of the
production and elimination of aqueous humour. Balanced IOP helps to maintain the eyeball …

Pregnancy and the eye

EWC Khong, HHL Chan, SL Watson… - Current Opinion in …, 2021 - journals.lww.com
Significant changes can occur to the eye during pregnancy, wherein the optimal treatment
for many ocular conditions remains uncertain, highlighting the need for further research to …

[HTML][HTML] Neuroprotective effect of omidenepag on excitotoxic retinal ganglion cell death regulating COX-2–EP2–cAMP–PKA/Epac pathway via Neuron–Glia interaction

N Nakamura, M Honjo, R Yamagishi-Kimura, R Sakata… - Neuroscience, 2024 - Elsevier
Glutamate excitotoxicity is involved in retinal ganglion cell (RGC) death in various retinal
degenerative diseases, including ischemia–reperfusion injury and glaucoma. Excitotoxic …

Primary congenital glaucoma in Denmark, 1977–2016

KB Pedersen, P Kappelgaard, L Kessel… - Acta …, 2020 - Wiley Online Library
Purpose To perform an epidemiological survey of all patients in Denmark diagnosed with
primary congenital glaucoma (PCG) from 1977 to 2016. Methods A retrospective, nationwide …

Short-Term and long-term variability of intraocular pressure measured with an intraocular telemetry sensor in patients with glaucoma

K Mansouri, HL Rao, RN Weinreb… - Ophthalmology, 2021 - Elsevier
Purpose To evaluate the short-term and long-term variability of intraocular pressure (IOP) in
eyes with primary open-angle glaucoma. Design Prospective study. Participants Twenty-two …

Association between sex hormones and visual field progression in women with primary open angle glaucoma: a cross-sectional and prospective cohort study

Y Qiu, J Yu, L Tang, J Ren, M Shao, S Li… - Frontiers in Aging …, 2021 - frontiersin.org
Purpose: We evaluated the level of sex hormones in female patients with primary open
angle glaucoma (POAG) to determine whether they are associated with the onset and/or …

[HTML][HTML] Identification of estrogen signaling in a prioritization study of intraocular pressure-associated genes

HA Youngblood, E Parker, J Cai, K Perkumas… - International journal of …, 2021 - mdpi.com
Elevated intraocular pressure (IOP) is the only modifiable risk factor for primary open-angle
glaucoma (POAG). Herein we sought to prioritize a set of previously identified IOP …

Girl power in glaucoma: the role of estrogen in primary open angle glaucoma

K Fotesko, BSV Thomsen, M Kolko, R Vohra - Cellular and Molecular …, 2022 - Springer
Estrogen is essential in maintaining various physiological features in women, and a decline
in estrogen levels are known to give rise to numerous unfortunate symptoms associated with …

Incidence of dementia in patients with open-angle glaucoma: a population-based study

AV Belamkar, SA Mansukhani, R Savica… - Journal of …, 2021 - journals.lww.com
Purpose: The aim was to determine the incidence of dementia and Alzheimer disease (AD)
among patients with OAG. Patients and Methods: Retrospective, population-based cohort …