Protein appetite as an integrator in the obesity system: the protein leverage hypothesis

D Raubenheimer, SJ Simpson - … Transactions of the …, 2023 - royalsocietypublishing.org
Despite the large volume and extensive range of obesity research, there is substantial
disagreement on the causes and effective preventative strategies. We suggest the field will …

Protein and amino acids in obesity: friends or foes?

Y Boirie, A Pinel, C Guillet - Current Opinion in Clinical Nutrition & …, 2023 - journals.lww.com
Interventions using dietary protein in obesity may be useful, especially during energy
restriction but also in sarcopenic obesity. Furthermore, metabolic profiles that encompass …

[HTML][HTML] Sucrose overconsumption impairs AgRP neuron dynamics and promotes palatable food intake

CM Lorch, NW Hayes, JL Xia, SW Fleps, HE McMorrow… - Cell reports, 2024 - cell.com
Rapid gut-brain communication is critical to maintain energy balance and is disrupted in diet-
induced obesity. In particular, the role of carbohydrate overconsumption in the regulation of …

No strong evidence of the protein leverage hypothesis in pregnant women with obesity and their infants

M Kebbe, J Most, AD Altazan, LM Redman - Obesity, 2023 - Wiley Online Library
Objective The goal of this study was to investigate the role of dietary protein on
macronutrient and energy intake, maternal adiposity during pregnancy, and infant adiposity …

[HTML][HTML] Asian Low-Carbohydrate Diet with Increased Whole Egg Consumption Improves Metabolic Outcomes in Metabolic Syndrome: A 52-Week Intervention Study

B Pinsawas, A Surawit, P Mongkolsucharitkul… - The Journal of …, 2024 - Elsevier
Background The low-carbohydrate-ketogenic diet, an effective strategy to address metabolic
syndrome (MetS) and obesity has raised concerns about high-fat consumption on …

Rapid benefits in older age from transition to whole food diet regardless of protein source or fat to carbohydrate ratio: Arandomised control trial

RV Ribeiro, AM Senior, SJ Simpson, J Tan… - Aging …, 2024 - Wiley Online Library
Plant‐based diets reduces the risk of chronic conditions. The interaction between protein
source and other macronutrients—fat (F) and carbohydrate (C)—has yet to be investigated …

Macronutrient composition of plant-based diets and breast cancer risk: the E3N prospective cohort study

NA Koemel, S Shah, AM Senior, G Severi… - European Journal of …, 2024 - Springer
Purpose Recent evidence suggests that plant-based diets may reduce the risk of breast
cancer (BC). However, the macronutrient composition of plant-based diets and its potential …

Evidence for the protein leverage hypothesis in preschool children prone to obesity

H Zhang, AM Senior, C Saner, NJ Olsen, SC Larsen… - Clinical Nutrition, 2023 - Elsevier
Background & aims The protein leverage hypothesis (PLH) proposed that strict regulation of
protein intake drives energy overconsumption and obesity when diets are diluted by fat …

Testing for Protein Leverage in Patients with Gastric Bypass: A Pilot Study

N Rodriguez-Murguiaa, JM Malacara… - Annals of Nutrition and …, 2023 - karger.com
Introduction: Protein leverage (PL) is the phenomenon whereby a dominant appetite for
protein drives overconsumption of energy with a decline in the ratio of protein to fat and …

[HTML][HTML] Utilisation des protéines et des acides aminés au cours de l'obésité

Y Boirie, A Pinel, C Guillet - Médecine des Maladies Métaboliques, 2024 - Elsevier
Résumé Les interventions nutritionnelles utilisant les protéines alimentaires sont largement
répandues dans l'obésité, en particulier lors de la restriction énergétique mais aussi en …