The last 10 years witnessed an acceleration of our understanding of what genetic factors
underpin the risk of breast cancer. Rare high-and moderate-penetrance variants such as …

Fibroblast growth factor receptor 2 (FGFR2) is a membrane-spanning tyrosine kinase that
mediates signaling for FGFs. Recent studies detected various point mutations of FGFR2 in …

Stromal stimuli mediated by growth factor receptors, leading to ligand-independent
activation of steroid hormone receptors, have long been implicated in development of breast …

Ear tip‐barrenness (ETB) phenotype threatens crop yield, because it reduces the kernel
number per ear. The genetic basis of ETB in maize remains largely unknown. Herein, a …

Background Menopausal status has a known relationship with the levels of estrogen,
progesterone, and other sex hormones, potentially influencing the activity of ER, PR, and …

Fibroblast growth factor receptor 2 (FGFR2) has been associated with breast cancer. We
performed in silico analyses to investigate the FGFR2 mRNA expression and splice variants …

Objective The aim of this article is to analyze and compare the presence of single-nucleotide
polymorphisms (SNPs) of COL1A1 and FGFR2 in class II and class III Javanese populations …

Expression of the tetraspanin CD151 is frequently upregulated in epithelial malignancies
and correlates with poor prognosis. Here, we report that CD151 is involved in regulation of …

Background Genome-wide association studies (GWAS) have to date identified 94 genetic
variants (single nucleotide polymorphisms (SNPs)) associated with risk of developing breast …

Aim Adjuvant clinical trials in early human epidermal growth factor receptor 2 (HER2)-
positive breast cancer have assessed either sequential or concomitant incorporation of …