Cellular signaling and factors involved in Müller cell gliosis: neuroprotective and detrimental effects

A Bringmann, I Iandiev, T Pannicke, A Wurm… - Progress in retinal and …, 2009 - Elsevier
Müller cells are active players in normal retinal function and in virtually all forms of retinal
injury and disease. Reactive Müller cells protect the tissue from further damage and …

A multifocal electroretinogram model predicting the development of diabetic retinopathy

MA Bearse Jr, AJ Adams, Y Han, ME Schneck… - Progress in retinal and …, 2006 - Elsevier
The prevalence of diabetes has been accelerating at an alarming rate in the last decade;
some describe it as an epidemic. Diabetic eye complications are the leading cause of …

[图书][B] Müller cells in the healthy and diseased retina

A Reichenbach, A Bringmann - 2010 - books.google.com
Müller glial cells ensheath all retinal neurons in vertebrate retinae. There are a multitude of
functional interactions between neurons and Müller cells, including delivery of the light …

A journey into the retina: Müller glia commanding survival and death

PV Subirada, MC Paz, ME Ridano… - European Journal of …, 2018 - Wiley Online Library
Müller glial cells (MGC s) are known to participate actively in retinal development and to
contribute to homoeostasis through many intracellular mechanisms. As there are no …

Mitogen‐activated protein kinase‐signaling regulates the ability of Müller glia to proliferate and protect retinal neurons against excitotoxicity

AJ Fischer, MA Scott, ER Ritchey, P Sherwood - Glia, 2009 - Wiley Online Library
The purpose of this study was to investigate whether insulin, fibroblast growth factor (FGF),
and mitogen-activated protein kinase (MAPK) pathways protect retinal neurons against …

Müller cells as a target for retinal therapy

J Devoldere, K Peynshaert, SC De Smedt… - Drug discovery today, 2019 - Elsevier
Highlights•This review reflects on the dual response of Müller cell after injury.•We review the
features that position Müller cells as a promising therapeutic target.•We discuss methods for …

[HTML][HTML] Insulin acts as a powerful stimulator of axial myopia in chicks

MP Feldkaemper, I Neacsu… - … ophthalmology & visual …, 2009 - arvojournals.org
purpose. In animal models, it has been shown that the retina can use the defocus of the
projected image to control emmetropization. Glucagon may be involved in the sign of …

Inhibition of high glucose-induced VEGF release in retinal ganglion cells by RNA interference targeting G protein-coupled receptor 91

J Hu, Q Wu, T Li, Y Chen, S Wang - Experimental eye research, 2013 - Elsevier
Recent research using a rat oxygen-induced retinopathy model has demonstrated that the G
protein-coupled receptor 91 (GPR91) of retinal ganglion neurons is the principal respondent …

Pharmacology of the retinal pigment epithelium, the interface between retina and body system

O Strauss - European journal of pharmacology, 2016 - Elsevier
The retinal pigment epithelium (RPE) is a close, interactive partner to the photoreceptors as
well as an interface with the endothelium of the choroid and thus with the body's circulatory …

[HTML][HTML] Fibrocontractive Muller cell phenotypes in proliferative diabetic retinopathy

C Guidry, JL King, JO Mason - Investigative ophthalmology & visual …, 2009 - arvojournals.org
purpose. To evaluate Müller cells as a potential source of fibrocontractive cells in
proliferative diabetic retinopathy. methods. Temporal changes in glial fibrillary acidic protein …