Familial Mediterranean fever, from pathogenesis to treatment: a contemporary review

A Tufan, H LACHMANN - Turkish Journal of Medical …, 2020 - journals.tubitak.gov.tr
Abstract Familial Mediterranean fever (FMF)(OMIM# 249100) is the most common hereditary
autoinflammatory disease in the world. FMF is caused by gain of function mutations of MEFV …

The clinical role of anakinra in the armamentarium against familial Mediterranean fever

K Parlar, MB Ates, BH Egeli… - Expert Review of Clinical …, 2024 - Taylor & Francis
ABSTRACT Introduction Familial Mediterranean Fever (FMF) is the most common
autoinflammatory disease that has mainly been treated with colchicine since 1972. A …

Real-life data from the largest pediatric familial Mediterranean fever cohort

K Öztürk, T Coşkuner, E Baglan, HE Sönmez… - Frontiers in …, 2022 - frontiersin.org
Familial Mediterranean fever (FMF) is the most common monogenic autoinflammatory
disease manifesting phenotypic heterogeneity. It is a clinically diagnosed disease supported …

PREDICT-crFMF score: a novel model for predicting colchicine resistance in children with familial Mediterranean fever

N Aktay Ayaz, FG Demirkan, T Coşkuner… - Modern …, 2024 - academic.oup.com
Objectives To develop a novel scoring system to predict colchicine resistance in Familial
Mediterranean fever (FMF) based on the initial features of the patients. Methods The medical …

The expanded spectrum of arthritis in children with familial Mediterranean fever

PO Avar-Aydın, ZB Ozcakar, F Aydın, HD Karakas… - Clinical …, 2022 - Springer
Abstract Introduction Familial Mediterranean fever (FMF) is the most common monogenic
autoinflammatory disease that can present with various forms of arthritis. This retrospective …

The Impact of Different MEFV Genotypes on Clinical Phenotype of Patients with Familial Mediterranean Fever: Special Emphasis on Joint Involvement

E Aslan, N Akay, U Gul, EK Konte, A Gunalp… - European Journal of …, 2024 - Springer
Abstract Familial Mediterranean Fever (FMF) is the most common monogenic
autoinflammatory disease worldwide. In this retrospective cohort study, we aimed to assess …

The pyrin inflammasome, a leading actor in pediatric autoinflammatory diseases

S La Bella, A Di Ludovico, G Di Donato… - Frontiers in …, 2024 - frontiersin.org
The activation of the pyrin inflammasome represents a highly intriguing mechanism
employed by the innate immune system to effectively counteract pathogenic agents. Despite …

Role of non-invasive methods in detecting liver impairment in familial Mediterranean fever adult patients with persistent hepatic cytolysis

S Deshayes, T Fraisse, S Fellahi, O Steichen… - Scientific Reports, 2022 - nature.com
Familial Mediterranean fever (FMF) patients may have hepatic cytolysis, although its origin is
not formally elucidated. We aimed to evaluate liver involvement in familial Mediterranean …

Inflammatory comorbidities ın the largest pediatric Familial Mediterranean fever cohort: a multicenter retrospective study of Pediatric Rheumatology Academy (PeRA) …

S Ozdel, T Coşkuner, F Demirkan, R Torun… - Clinical …, 2024 - Springer
Aim The aim of this study was to investigate the frequency and type of FMF-associated
inflammatory diseases in a large FMF pediatric patients and to compare them to those FMF …

Not easy-peasy to diagnose: familial Mediterranean fever unaccompanied by fever

SD Arık, GK Kayaalp, V Guliyeva, FG Demirkan… - European Journal of …, 2023 - Springer
Classical attacks of familial Mediterranean fever (FMF) are often accompanied by fever, but
some of the patients have attacks without fever. This study aimed to compare the …