Toward better understanding of artifacts in variant calling from high-coverage samples
H Li - Bioinformatics, 2014 - academic.oup.com
Motivation: Whole-genome high-coverage sequencing has been widely used for personal
and cancer genomics as well as in various research areas. However, in the lack of an …
and cancer genomics as well as in various research areas. However, in the lack of an …
Genotyping‐by‐sequencing approaches to characterize crop genomes: choosing the right tool for the right application
In the last decade, the revolution in sequencing technologies has deeply impacted crop
genotyping practice. New methods allowing rapid, high‐throughput genotyping of entire …
genotyping practice. New methods allowing rapid, high‐throughput genotyping of entire …
Comprehensive evaluation and characterisation of short read general-purpose structural variant calling software
In recent years, many software packages for identifying structural variants (SVs) using whole-
genome sequencing data have been released. When published, a new method is commonly …
genome sequencing data have been released. When published, a new method is commonly …
Development and evaluation of a barley 50k iSelect SNP array
MM Bayer, P Rapazote-Flores, M Ganal… - Frontiers in plant …, 2017 - frontiersin.org
High-throughput genotyping arrays continue to be an attractive, cost-effective alternative to
sequencing based approaches. We have developed a new 50k Illumina Infinium iSelect …
sequencing based approaches. We have developed a new 50k Illumina Infinium iSelect …
Evaluation of hybridization capture versus amplicon‐based methods for whole‐exome sequencing
E Samorodnitsky, BM Jewell, R Hagopian… - Human …, 2015 - Wiley Online Library
Next‐generation sequencing has aided characterization of genomic variation. While whole‐
genome sequencing may capture all possible mutations, whole‐exome sequencing remains …
genome sequencing may capture all possible mutations, whole‐exome sequencing remains …
The African turquoise killifish genome provides insights into evolution and genetic architecture of lifespan
Lifespan is a remarkably diverse trait ranging from a few days to several hundred years in
nature, but the mechanisms underlying the evolution of lifespan differences remain elusive …
nature, but the mechanisms underlying the evolution of lifespan differences remain elusive …
Review of current methods, applications, and data management for the bioinformatics analysis of whole exome sequencing
The advent of next-generation sequencing technologies has greatly promoted advances in
the study of human diseases at the genomic, transcriptomic, and epigenetic levels. Exome …
the study of human diseases at the genomic, transcriptomic, and epigenetic levels. Exome …
Comparison of exome and genome sequencing technologies for the complete capture of protein‐coding regions
For next‐generation sequencing technologies, sufficient base‐pair coverage is the foremost
requirement for the reliable detection of genomic variants. We investigated whether whole …
requirement for the reliable detection of genomic variants. We investigated whether whole …
The GATK joint genotyping workflow is appropriate for calling variants in RNA-seq experiments
JS Brouard, F Schenkel, A Marete… - Journal of animal science …, 2019 - Springer
Abstract The Genome Analysis Toolkit (GATK) is a popular set of programs for discovering
and genotyping variants from next-generation sequencing data. The current GATK …
and genotyping variants from next-generation sequencing data. The current GATK …
Fluoxetine regulates eEF2 activity (phosphorylation) via HDAC1 inhibitory mechanism in an LPS-induced mouse model of depression
Background Selective serotonin reuptaker inhibitors, including fluoxetine, are widely studied
and prescribed antidepressants, while their exact molecular and cellular mechanism are yet …
and prescribed antidepressants, while their exact molecular and cellular mechanism are yet …