The role of the gut microbiota in health and cardiovascular diseases

L Wang, S Wang, Q Zhang, C He, C Fu, Q Wei - Molecular biomedicine, 2022 - Springer
The gut microbiota is critical to human health, such as digesting nutrients, forming the
intestinal epithelial barrier, regulating immune function, producing vitamins and hormones …

Integrated metagenomic and metabolomic analysis reveals distinct gut-microbiome-derived phenotypes in early-onset colorectal cancer

C Kong, L Liang, G Liu, L Du, Y Yang, J Liu, D Shi, X Li… - Gut, 2023 - gut.bmj.com
Objective The incidence of early-onset colorectal cancer (EO-CRC) is steadily increasing.
Here, we aimed to characterise the interactions between gut microbiome, metabolites and …

The accumulation and molecular effects of trimethylamine N-oxide on metabolic tissues: It's not all bad

ES Krueger, TS Lloyd, JS Tessem - Nutrients, 2021 - mdpi.com
Since elevated serum levels of trimethylamine N-oxide (TMAO) were first associated with
increased risk of cardiovascular disease (CVD), TMAO research among chronic diseases …

Gut dysbiosis in stroke and its implications on Alzheimer's disease‐like cognitive dysfunction

J Cho, YJ Park, B Gonzales‐Portillo… - CNS Neuroscience …, 2021 - Wiley Online Library
Various neurological disorders, such as stroke and Alzheimer's disease (AD), involve
neuroinflammatory responses. The advent of the gut‐brain axis enhances our …

The Triple Alliance: Microbiome, Mitochondria, and Metabolites in the Context of Age-Related Cognitive Decline and Alzheimer's Disease

SK Prajapati, R Shah, N Alford… - The Journals of …, 2023 - academic.oup.com
Alzheimer's disease (AD) is a progressive, age-related neurodegenerative disorder that
affects a large proportion of the older population. It currently lacks effective treatments …

Intestinal permeability, gut inflammation, and gut immune system response are linked to aging-related changes in gut microbiota composition: a study in female mice

PE Gámez-Macías, E Félix-Soriano… - The Journals of …, 2024 - academic.oup.com
Aging entails changes at the cellular level that increase the risk of various pathologies. An
association between gut microbiota and age-related diseases has also been attributed. This …

Role of butyrogenic Firmicutes in type-2 diabetes

MM James, N Pal, P Sharma, M Kumawat… - Journal of Diabetes & …, 2022 - Springer
Objective The aim of this review is to speculate the pre-clinical and clinical evidences
indicating the association between butyrate-synthesizing firmicutes and development and …

Plasma taurine level is linked to symptom burden and clinical outcomes in post-COVID condition

M Khoramjoo, K Wang, K Srinivasan, M Gheblawi… - Plos one, 2024 - journals.plos.org
Background A subset of individuals (10–20%) experience post-COVID condition (PCC)
subsequent to initial SARS-CoV-2 infection, which lacks effective treatment. PCC carries a …

[HTML][HTML] Probiotics treatment for Parkinson disease: a systematic review and meta-analysis of clinical trials

CT Hong, JH Chen, TW Huang - Aging (Albany NY), 2022 - ncbi.nlm.nih.gov
Background and aims: People with Parkinson disease (PwP) exhibit gut dysbiosis and
considerable gastrointestinal (GI) symptoms. Probiotics, beneficial strains of …

Probiotics as a targeted intervention in anti-ageing: a review

F Shi, J Peng, H Li, D Liu, L Han, Y Wang, Q Liu… - Biomarkers, 2024 - Taylor & Francis
Context The age-induced disruption of gut flora, termed gut dysbiosis, is intimately tied to
compromised immune function, augmented oxidative stress and a spectrum of age-linked …