Inflammation is currently considered a prime target for the development of new stroke
therapies. In the acute phase of ischemic stroke, microglia are activated and then circulating …

Inflammation is increasingly recognized as being of both physiological and pathological
importance in the immature brain. The rationale of this review is to present an update on this …

Microglia mediate multiple facets of neuroinflammation, including cytotoxicity, repair,
regeneration, and immunosuppression due to their ability to acquire diverse activation …

Despite dramatic improvements in the management of traumatic brain injury (TBI), to date
there is no effective treatment available to patients, and morbidity and mortality remain high …

Perinatal hypoxia-ischemia remains the primary cause of acute neonatal brain injury,
leading to a high mortality rate and long-term neurological deficits, such as behavioral …

Inflammation plays a critical role in mediating brain injury induced by neonatal hypoxic
ischemic encephalopathy (HIE). The mechanisms underlying inflammatory responses to …

With the contribution from more than one hundred CNS neurotrauma experts, this book
provides a comprehensive and up-to-date account on the latest developments in the area of …

The precise role of maternal bacterial infection and inflammation occurring at the end of
gestation is a controversial matter. Although it is recognized as an independent risk factor for …

Following focal cerebral ischemia (“stroke”) a complex and dynamic interaction of vascular
cells, glial cells, and neurons determines the extent of the ensuing lesion. Traditionally, the …

Preterm birth is an evolving challenge in neonatal health care. Despite declining mortality
rates among extremely premature neonates, morbidity rates remain very high. Currently …