Single-virus tracking: from imaging methodologies to virological applications

SL Liu, ZG Wang, HY Xie, AA Liu, DC Lamb… - Chemical …, 2020 - ACS Publications
Uncovering the mechanisms of virus infection and assembly is crucial for preventing the
spread of viruses and treating viral disease. The technique of single-virus tracking (SVT) …

[HTML][HTML] Biocompatible quantum dots for biological applications

SJ Rosenthal, JC Chang, O Kovtun, JR McBride… - Chemistry & biology, 2011 - cell.com
Semiconductor quantum dots are quickly becoming a critical diagnostic tool for discerning
cellular function at the molecular level. Their high brightness, long-lasting, size-tunable, and …

Deleterious effects of amyloid β oligomers acting as an extracellular scaffold for mGluR5

M Renner, PN Lacor, PT Velasco, J Xu, A Contractor… - Neuron, 2010 - cell.com
Soluble oligomers of amyloid β (Aβ) play a role in the memory impairment characteristic of
Alzheimer's disease. Acting as pathogenic ligands, Aβ oligomers bind to particular synapses …

In situ visualization and dynamics of newly synthesized proteins in rat hippocampal neurons

DC Dieterich, JJL Hodas, G Gouzer, IY Shadrin… - Nature …, 2010 - nature.com
Protein translation has been implicated in different forms of synaptic plasticity, but direct in
situ visualization of new proteins is limited to one or two proteins at a time. Here we describe …

Convergence of adenosine and GABA signaling for synapse stabilization during development

F Gomez-Castro, S Zappettini, JC Pressey, CG Silva… - Science, 2021 - science.org
INTRODUCTION During development, brain circuits go through phases of synapse
formation, stabilization, or elimination. γ-aminobutyric acid–mediated (GABAergic) synapse …

Probing cellular events, one quantum dot at a time

F Pinaud, S Clarke, A Sittner, M Dahan - Nature methods, 2010 - nature.com
Monitoring the behavior of single molecules in living cells is a powerful approach to
investigate the details of cellular processes. Owing to their optical, chemical and …

Bioconjugated quantum dots for multiplexed and quantitative immunohistochemistry

Y Xing, Q Chaudry, C Shen, KY Kong, HE Zhau… - Nature protocols, 2007 - nature.com
Bioconjugated quantum dots (QDs) provide a new class of biological labels for evaluating
biomolecular signatures (biomarkers) on intact cells and tissue specimens. In particular, the …

Second harmonic generating (SHG) nanoprobes for in vivo imaging

P Pantazis, J Maloney, D Wu… - Proceedings of the …, 2010 - National Acad Sciences
Fluorescence microscopy has profoundly changed cell and molecular biology studies by
permitting tagged gene products to be followed as they function and interact. The ability of a …

Dynamic heterogeneity and non-Gaussian statistics for acetylcholine receptors on live cell membrane

W He, H Song, Y Su, L Geng, BJ Ackerson… - Nature …, 2016 - nature.com
The Brownian motion of molecules at thermal equilibrium usually has a finite correlation time
and will eventually be randomized after a long delay time, so that their displacement follows …

Role of the neuronal K-Cl co-transporter KCC2 in inhibitory and excitatory neurotransmission

I Chamma, Q Chevy, JC Poncer, S Lévi - Frontiers in cellular …, 2012 - frontiersin.org
The K-Cl co-transporter KCC2 plays multiple roles in the physiology of central neurons and
alterations of its function and/or expression are associated with several neurological …