Vitamin D and the brain: Genomic and non-genomic actions

X Cui, H Gooch, A Petty, JJ McGrath, D Eyles - Molecular and cellular …, 2017 - Elsevier
Abstract 1, 25 (OH) 2 D 3 (vitamin D) is well-recognized as a neurosteroid that modulates
multiple brain functions. A growing body of evidence indicates that vitamin D plays a pivotal …

Vitamin D in neurological diseases: a rationale for a pathogenic impact

R Moretti, ME Morelli, P Caruso - International journal of molecular …, 2018 - mdpi.com
It is widely known that vitamin D receptors have been found in neurons and glial cells, and
their highest expression is in the hippocampus, hypothalamus, thalamus and subcortical …

Vitamin D and its role in the lipid metabolism and the development of atherosclerosis

AM Surdu, O Pînzariu, DM Ciobanu, AG Negru… - Biomedicines, 2021 - mdpi.com
Vitamin D, a crucial hormone in the homeostasis and metabolism of calcium bone, has lately
been found to produce effects on other physiological and pathological processes …

Vitamin D and Parkinson's disease

A Pignolo, S Mastrilli, C Davì, V Arnao, P Aridon… - Nutrients, 2022 - mdpi.com
Vitamin D is a fat-soluble secosteroid, traditionally considered a key regulator of bone
metabolism, calcium and phosphorous homeostasis. Its action is made possible through the …

Novel insights into the molecular mechanisms of atherosclerosis

A Wojtasińska, W Frąk, W Lisińska, N Sapeda… - International journal of …, 2023 - mdpi.com
Atherosclerosis is one of the most fatal diseases in the world. The associated thickening of
the arterial wall and its background and consequences make it a very composite disease …

The peculiar role of vitamin D in the pathophysiology of cardiovascular and neurodegenerative diseases

M Janjusevic, G Gagno, AL Fluca, L Padoan… - Life sciences, 2022 - Elsevier
Vitamin D is a hormone with both genomic and non-genomic actions. It exerts its activity by
binding vitamin D receptor (VDR), which belongs to the superfamily of nuclear receptors and …

Vitamin D deficiency and the risk of cerebrovascular disease

HA Kim, A Perrelli, A Ragni, F Retta, TM De Silva… - Antioxidants, 2020 - mdpi.com
Vitamin D deficiency has been clearly linked to major chronic diseases associated with
oxidative stress, inflammation, and aging, including cardiovascular and neurodegenerative …

Health risks of hypovitaminosis D: a review of new molecular insights

D Caccamo, S Ricca, M Currò, R Ientile - International journal of …, 2018 - mdpi.com
Hypovitaminosis D has become a pandemic, being observed in all ethnicities and age
groups worldwide. Environmental factors, such as increased air pollution and reduced …

Lower vitamin D status is associated with an increased risk of ischemic stroke: a systematic review and meta-analysis

R Zhou, M Wang, H Huang, W Li, Y Hu, T Wu - Nutrients, 2018 - mdpi.com
In recent years, accumulating evidence has supported the hypothesis that lower vitamin D
status is associated with several known risk factors of stroke. However, the relationship …

Vitamin D3 and ischemic stroke: a narrative review

W Lasoń, D Jantas, M Leśkiewicz, M Regulska… - Antioxidants, 2022 - mdpi.com
Ischemic stroke is one of the major causes of death and permanent disability worldwide. The
only efficient treatment to date is anticoagulant therapy and thrombectomy, which enable …