Trends in the development of miRNA bioinformatics tools

L Chen, L Heikkinen, C Wang, Y Yang… - Briefings in …, 2019 - academic.oup.com
MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression via
recognition of cognate sequences and interference of transcriptional, translational or …

Nuclear functions of mammalian MicroRNAs in gene regulation, immunity and cancer

H Liu, C Lei, Q He, Z Pan, D Xiao, Y Tao - Molecular cancer, 2018 - Springer
MicroRNAs (miRNAs) are endogenous non-coding RNAs that contain approximately 22
nucleotides. They serve as key regulators in various biological processes and their …

miRWalk: an online resource for prediction of microRNA binding sites

C Sticht, C De La Torre, A Parveen, N Gretz - PloS one, 2018 - journals.plos.org
miRWalk is an open-source platform providing an intuitive interface that generates predicted
and validated miRNA-binding sites of known genes of human, mouse, rat, dog and cow. The …

mirDIP 4.1—integrative database of human microRNA target predictions

T Tokar, C Pastrello, AEM Rossos… - Nucleic acids …, 2018 - academic.oup.com
MicroRNAs are important regulators of gene expression, achieved by binding to the gene to
be regulated. Even with modern high-throughput technologies, it is laborious and expensive …

MicroRNA regulatory networks in human adipose tissue and obesity

P Arner, A Kulyté - Nature Reviews Endocrinology, 2015 - nature.com
MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression and,
therefore, biological processes in different tissues. A major function of miRNAs in adipose …

Common features of microRNA target prediction tools

SM Peterson, JA Thompson, ML Ufkin… - Frontiers in …, 2014 - frontiersin.org
The human genome encodes for over 1800 microRNAs (miRNAs), which are short non-
coding RNA molecules that function to regulate gene expression post-transcriptionally. Due …

MicroRNAs and cancer: Key paradigms in molecular therapy

W Tan, B Liu, S Qu, G Liang, W Luo… - Oncology …, 2018 - spandidos-publications.com
MicroRNAs (miRNAs) are a type of small non-coding RNA molecule that performs an
important role in post‑transcriptional gene regulation. Since miRNAs were first identified in …

Identifying miRNAs, targets and functions

B Liu, J Li, MJ Cairns - Briefings in bioinformatics, 2014 - academic.oup.com
Abstract microRNAs (miRNAs) are small endogenous non-coding RNAs that function as the
universal specificity factors in post-transcriptional gene silencing. Discovering miRNAs …

MicroRNAs in common human diseases

Y Li, KV Kowdley - Genomics, Proteomics and Bioinformatics, 2012 - academic.oup.com
MicroRNAs (miRNAs) are a class of short non-coding RNA molecules that have attracted
tremendous attention from the biological and biomedical research communities over the …

The role of let-7 in cell differentiation and cancer

B Boyerinas, SM Park, A Hau… - Endocrine-related …, 2010 - erc.bioscientifica.com
MicroRNAs (miRNAs or miRs) are small noncoding RNAs capable of regulating gene
expression at the translational level. Current evidence suggests that a significant portion of …