Design, optimization, and nanotechnology of antimicrobial peptides: From exploration to applications

P Tan, H Fu, X Ma - Nano Today, 2021 - Elsevier
Antibiotic resistance caused by antibiotic abuse, especially the emergence of multi-drug
resistant bacteria, poses a serious threat to human health, and makes it imperative to find …

Smart cancer nanomedicine

R van der Meel, E Sulheim, Y Shi, F Kiessling… - Nature …, 2019 - nature.com
Nanomedicines are extensively employed in cancer therapy. We here propose four strategic
directions to improve nanomedicine translation and exploitation.(1) Patient stratification has …

Chemically programmed STING-activating nano-liposomal vesicles improve anticancer immunity

X Chen, F Meng, Y Xu, T Li, X Chen, H Wang - Nature Communications, 2023 - nature.com
The often immune-suppressive tumor microenvironment (TME) may hinder immune evasion
and response to checkpoint blockade therapies. Pharmacological activation of the STING …

Nanotechnology for COVID-19: therapeutics and vaccine research

G Chauhan, MJ Madou, S Kalra, V Chopra, D Ghosh… - ACS …, 2020 - ACS Publications
The current global health threat by the novel coronavirus disease 2019 (COVID-19) requires
an urgent deployment of advanced therapeutic options available. The role of …

Small‐molecule prodrug nanoassemblies: an emerging nanoplatform for anticancer drug delivery

G Li, B Sun, Y Li, C Luo, Z He, J Sun - Small, 2021 - Wiley Online Library
The antitumor efficiency and clinical translation of traditional nanomedicines is mainly
restricted by low drug loading, complex preparation technology, and potential toxicity …

Nanoscale self-assembly for therapeutic delivery

S Yadav, AK Sharma, P Kumar - Frontiers in Bioengineering and …, 2020 - frontiersin.org
Self-assembly is the process of association of individual units of a material into highly
arranged/ordered structures/patterns. It imparts unique properties to both inorganic and …

Stimuli‐responsive nanotherapeutics for precision drug delivery and cancer therapy

Y Qiao, J Wan, L Zhou, W Ma, Y Yang… - Wiley …, 2019 - Wiley Online Library
Cancer remains one of the world's leading causes of death. However, most conventional
chemotherapeutic drugs only show a narrow therapeutic window in patients because of their …

Engineering prodrug nanomedicine for cancer immunotherapy

B Yang, J Gao, Q Pei, H Xu, H Yu - Advanced Science, 2020 - Wiley Online Library
Immunotherapy has shifted the clinical paradigm of cancer management. However, despite
promising initial progress, immunotherapeutic approaches to cancer still suffer from …

Resveratrol-loaded PLGA nanoparticles: enhanced stability, solubility and bioactivity of resveratrol for non-alcoholic fatty liver disease therapy

S Wan, L Zhang, Y Quan, K Wei - Royal Society open …, 2018 - royalsocietypublishing.org
Resveratrol (3, 4′, 5-trihydroxy-trans-stilbene, RSV), a nutraceutical, has recently attracted
lots of attention because of its outstanding pharmacological potential. The effects of RSV on …

Platinum (iv) prodrugs with long lipid chains for drug delivery and overcoming cisplatin resistance

Q Chen, Y Yang, X Lin, W Ma, G Chen, W Li… - Chemical …, 2018 - pubs.rsc.org
Platinum( iv ) prodrugs with long lipid chains for drug delivery and overcoming cisplatin
resistance - Chemical Communications (RSC Publishing) DOI:10.1039/C8CC02791A Royal …