Neurobehavioural comorbidities of epilepsy: towards a network-based precision taxonomy
Cognitive and behavioural comorbidities are prevalent in childhood and adult epilepsies
and impose a substantial human and economic burden. Over the past century, the classic …
and impose a substantial human and economic burden. Over the past century, the classic …
Mechanisms of action of antiseizure drugs and the ketogenic diet
MA Rogawski, W Löscher… - Cold Spring …, 2016 - perspectivesinmedicine.cshlp.org
Antiseizure drugs (ASDs), also termed antiepileptic drugs, are the main form of symptomatic
treatment for people with epilepsy, but not all patients become free of seizures. The …
treatment for people with epilepsy, but not all patients become free of seizures. The …
Altered functional–structural coupling of large-scale brain networks in idiopathic generalized epilepsy
The human brain is a large-scale integrated network in the functional and structural domain.
Graph theoretical analysis provides a novel framework for analysing such complex …
Graph theoretical analysis provides a novel framework for analysing such complex …
Impaired consciousness in epilepsy
H Blumenfeld - The Lancet Neurology, 2012 - thelancet.com
Consciousness is essential to normal human life. In epileptic seizures consciousness is
often transiently lost, which makes it impossible for the individual to experience or respond …
often transiently lost, which makes it impossible for the individual to experience or respond …
Altered functional connectivity and small-world in mesial temporal lobe epilepsy
Background The functional architecture of the human brain has been extensively described
in terms of functional connectivity networks, detected from the low–frequency coherent …
in terms of functional connectivity networks, detected from the low–frequency coherent …
Neuroimaging of epilepsy
Imaging is pivotal in the evaluation and management of patients with seizure disorders.
Elegant structural neuroimaging with magnetic resonance imaging (MRI) may assist in …
Elegant structural neuroimaging with magnetic resonance imaging (MRI) may assist in …
Mapping lesion-related epilepsy to a human brain network
Importance It remains unclear why lesions in some locations cause epilepsy while others do
not. Identifying the brain regions or networks associated with epilepsy by mapping these …
not. Identifying the brain regions or networks associated with epilepsy by mapping these …
Cerebellar directed optogenetic intervention inhibits spontaneous hippocampal seizures in a mouse model of temporal lobe epilepsy
Abstract Cover Figure Krook-Magnuson et al. report a bidirectional functional connectivity
between the hippocampus and the cerebellum in a mouse model of temporal lobe epilepsy …
between the hippocampus and the cerebellum in a mouse model of temporal lobe epilepsy …
The postictal state—What do we know?
JCM Pottkämper, J Hofmeijer, JA van Waarde… - …, 2020 - Wiley Online Library
This narrative review provides a broad and comprehensive overview of the most important
discoveries on the postictal state over the past decades as well as recent developments …
discoveries on the postictal state over the past decades as well as recent developments …
Ictal high frequency oscillations distinguish two types of seizure territories in humans
High frequency oscillations have been proposed as a clinically useful biomarker of seizure
generating sites. We used a unique set of human microelectrode array recordings (four …
generating sites. We used a unique set of human microelectrode array recordings (four …