In this review, we discuss the effects on androgens on the haemopoietic system, focussing
largely on the effects of testosterone on erythropoiesis. Stimulation of erythropoiesis is one …

Telomeres are unique structures located at the ends of linear chromosomes, responsible for
stabilizing chromosomal structures. They are synthesized by telomerase, a reverse …

Telomeres are localized at the end of chromosomes to provide genome stability; however,
the telomere length tends to be shortened with each cell division inducing a progressive …

Telomere biology disorders (TBDs) are a spectrum of inherited bone marrow failure
syndromes caused by impaired telomere function due to pathogenic germline variants in …

Telomeropathies or telomere biology disorders (TBDs) are a group of rare diseases
characterised by altered telomere maintenance. Most patients with TBDs show pathogenic …

A five-membered N–O heterocycle, 4, 5-dihydro-1, 2, 4-oxadiazole, was found to act as a
single nitrogen atom transfer reagent via elimination of a ketone/aldehyde and a nitrile. This …

Background: Telomeres are the end-capping structures of all eukaryotic chromosomes
thereby protecting the genome from damage and degradation. During the aging process …

Dyskeratosis congenital (DC) is the first genetic syndrome described among
telomeropathies. Its classical phenotype is characterized by the mucocutaneous triad of …

Androgens represent the historical therapeutic backbone of bone marrow failure (BMF)
syndromes. However, their role has rarely been analyzed in a prospective setting, and …

Carriers of germline telomerase‐related gene (TRG) mutations can show poor prognosis,
with an increase in common hematological complications after lung transplantation (LT) for …