Inflammation clearly occurs in pathologically vulnerable regions of the Alzheimer's disease
(AD) brain, and it does so with the full complexity of local peripheral inflammatory responses …

Early reviews identified over 20 risk factors associated with Alzheimer's disease (AD)
including age, familial inheritance, exposure to aluminium, traumatic brain injury (TBI), and …

Since the earliest descriptions of Alzheimer's disease (AD), many theories have been
advanced as to its cause. These include:(1) exacerbation of aging,(2) degeneration of …

Methods. Subjects. All were enrolled as healthy elderly control subjects in a longitudinal
study of DAT for which the recruitment, entry characteristics, and assessment methods have …

In a sample of consecutively received, 4 demented and 4 age‐matched nondemented
brains, the total cortical area covered by plaque‐like Aβ amyloid and butyrylcholinesterase …

Anti-inflammatory drugs have been suggested as a possible treatment for Alzheimer's
disease (AD). The association of immune proteins and immune-competent microglial cells …

Alzheimer's disease is associated with a specific pattern of pathological changes in the brain
that result in neurodegeneration and the progressive development of dementia. Pathological …

Histochemical analysis of Alzheimer disease (AD) brain tissues indicates that
butyrylcholinesterase (BuChE) is present in β-amyloid (Aβ) plaques. The role of BuChE in …

To assess the role of microglial cells in senile plaque (SP) formation, we examined the
density and distribution of microglia in the temporal neocortex of three groups of …

The incidence, distribution and chemical composition of amyloid-β (Aβ) peptide-positive
deposits were investigated in the lower primate species common marmoset (Callithrix …