Investigations of the use of in vitro cytotoxicity tests for the prediction of acute toxicity in vivo
have been reviewed with particular emphasis on those studies that have been published …

In this study, the association between the acute toxicity of 15 compounds to Daphnia magna,
expressed as 24-and 48-h LC50 values, and the corresponding oral LD50 values for the rat …

During the last 20years, in vitro assays with fish cells have been used in ecotoxicology for
testing chemicals, effluents and in toxicity identification evaluations (TIE) studies. Due to the …

The accurate assessment of cytotoxicity is important for evaluating the potential of a test
agent to induce pathologies that result from cell killing and to determine appropriate doses …

Cytotoxicity studies are a useful initial step in determining the potential toxicity of a test
substance, including plant extracts or biologically active compounds isolated from plants …

Developments in cell culture and in bioanalytical and computer technology have resulted in
the rapid proliferation of new procedures for use in the hazard evaluation of chemicals (1) …

In this study the focus is on the comparison of fluorometric assays, using Alamar Blue (AB)
and Hoechst 33342 coloration, and luminometric assays, using Cyto-Lite and ATP-Lite, for …

Results from tests of the first 30 MEIC reference chemicals in 68 different toxicity assays are
presented as a prerequisite to subsequent in vitro/in vivo comparisons of acute toxicity data …

The Multicenter Evaluation of In Vitro Cytotoxicity (MEIC) programme was set up to evaluate
the relevance for human acute toxicity of in vitro cytotoxicity tests. At the end of the project in …

First Published in 1994, Introduction to In Vitro Cytotoxicology examines in vitro
cytotoxicology, which offers new methodologies to toxicity testing. This important new …