DNA vaccines for SARS-CoV-2: toward third-generation vaccination era

VP Chavda, R Pandya… - Expert Review of …, 2021 - Taylor & Francis
ABSTRACT Introduction: Coronavirus outbreak 2019 (COVID-19) has affected all the
corners of the globe and created chaos to human life. In order to put some control on the …

A brief review on DNA vaccines in the era of COVID-19

M Shafaati, M Saidijam, M Soleimani, F Hazrati… - Future …, 2022 - Taylor & Francis
This article provides a brief overview of DNA vaccines. First, the basic DNA vaccine design
strategies are described, then specific issues related to the industrial production of DNA …

Rise of the RNA machines–self-amplification in mRNA vaccine design

JDG Comes, GP Pijlman, TAH Hick - Trends in Biotechnology, 2023 - cell.com
Abstract mRNA vaccines have won the race for early COVID-19 vaccine approval, yet
improvements are necessary to retain this leading role in combating infectious diseases. A …

Technologies for enhanced efficacy of DNA vaccines

F Saade, N Petrovsky - Expert review of vaccines, 2012 - Taylor & Francis
Despite many years of research, human DNA vaccines have yet to fulfill their early promise.
Over the past 15 years, multiple generations of DNA vaccines have been developed and …

Cancer vaccines, treatment of the future: with emphasis on HER2-positive breast cancer

S Pallerla, ARM Abdul, J Comeau, S Jois - International journal of …, 2021 - mdpi.com
Breast cancer is one of the leading causes of death in women. With improvements in early-
stage diagnosis and targeted therapies, there has been an improvement in the overall …

[HTML][HTML] Breast cancer vaccines: New insights into immunomodulatory and nano-therapeutic approaches

F Davodabadi, M Sarhadi, J Arabpour, S Sargazi… - Journal of Controlled …, 2022 - Elsevier
Breast cancer (BC) is known to be a highly heterogeneous disease that is clinically
subdivided into four primary molecular subtypes, each having distinct morphology and …

Functionalized gold nanoparticles for the binding, stabilization, and delivery of therapeutic DNA, RNA, and other biological macromolecules

RK DeLong, CM Reynolds, Y Malcolm… - Nanotechnology …, 2010 - Taylor & Francis
Nanotechnology has virtually exploded in the last few years with seemingly limitless
opportunity across all segments of our society. If gene and RNA therapy are to ever realize …

Non-viral nucleic acid delivery: key challenges and future directions

M Elsabahy, A Nazarali, M Foldvari - Current drug delivery, 2011 - ingentaconnect.com
Gene therapy holds the promise of correcting a genetic defect. It can be achieved with the
introduction of a normal wild-type transgene into specific cells of the patient where the …

Vector design for improved DNA vaccine efficacy, safety and production

JA Williams - Vaccines, 2013 - mdpi.com
DNA vaccination is a disruptive technology that offers the promise of a new rapidly deployed
vaccination platform to treat human and animal disease with gene-based materials …

Enhancing therapeutic performance of personalized cancer vaccine via delivery vectors

T Ye, F Li, G Ma, W Wei - Advanced drug delivery Reviews, 2021 - Elsevier
In recent years, personalized cancer vaccines have gained increasing attention as emerging
immunotherapies with the capability to overcome interindividual differences and show great …