Lyophilization is a promising approach to ensure the long-term stability of liposomes. After
decades of studies in this field, different lyoprotective mechanisms, such as water …

Buffers comprise an integral component of protein formulations. Not only do they function to
regulate shifts in pH, they also can stabilize proteins by a variety of mechanisms. The ability …

Freeze‐drying (lyophilization) removes water from a frozen sample by sublimation and
desorption. It can be viewed as a three‐step process consisting of freezing, primary drying …

Extracellular vesicles (EVs) have been studied for years for their role as effectors and
mediators of cell-to-cell communication and their potential application to develop new and …

The goal was to investigate the impact of NaCl on the physico-chemical properties of
mannitol–sucrose formulations during freezing and drying, with special focus on mannitol …

In this study, a new and robust method was evaluated to prepare physically stable solid
dispersions. Trehalose, sucrose, and two inulins having different chain lengths were used as …

Purpose. The aim of the present work is to study the interaction of phosphate salts with
trehalose and sucrose in freeze-dried matrices, particularly the effect of the salts on the glass …

The octanol–water partition coefficients (P) of glucose, sucrose, and trehalose were
measured at temperatures between 5 and 20° C using an enzymatic method. The measured …

The purpose of the present work was to analyze the effect of trehalose, arabic and guar
gums on the preservation of β-galactosidase activity in freeze-dried and vacuum dried Ca (II) …

The current study offers a blend of volumetric and acoustic approaches to examine the
interlinkage between homologous series of glycol molecules (ethylene glycol (EG) …