Congenital diaphragmatic hernia

JA Tovar - Orphanet journal of rare diseases, 2012 - Springer
Abstract Congenital Diaphragmatic Hernia (CDH) is defined by the presence of an orifice in
the diaphragm, more often left and posterolateral that permits the herniation of abdominal …

Congenital heart disease associated with congenital diaphragmatic hernia: a systematic review on incidence, prenatal diagnosis, management, and outcome

L Montalva, G Lauriti, A Zani - Journal of pediatric surgery, 2019 - Elsevier
Purpose The purpose of this study was to evaluate the impact of congenital heart disease
(CHD) on infants with congenital diaphragmatic hernia (CDH). Methods Using a defined …

Mechanisms of action of the congenital diaphragmatic hernia-inducing teratogen nitrofen

BR Noble, RP Babiuk, RD Clugston… - … of Physiology-Lung …, 2007 - journals.physiology.org
Congenital diaphragmatic hernia (CDH) is a developmental anomaly that results in
significant mortality and morbidity. The underlying etiology is poorly understood. Insights will …

Lung development following diaphragmatic hernia in the fetal rabbit

J Wu, H Yamamoto, E Gratacos, X Ge… - Human …, 2000 - academic.oup.com
Diaphragmatic hernia was created in 39 rabbit fetuses on day 23 of gestation. Fifteen
fetuses underwent a sham thoracotomy (SHAM). Thirty-nine non-operated littermates served …

Animal models in pediatric surgery

A Mortell, S Montedonico, P Puri - Pediatric surgery international, 2006 - Springer
The advent of animal models of pediatric surgical diseases has not only allowed us to study
the etiology and pathogenesis of complex congenital anomalies but has also led to major …

Pulmonary effects of in utero tracheal occlusion are dependent on gestational age in a rabbit model of diaphragmatic hernia

J Wu, X Ge, EK Verbeken, E Gratacós… - Journal of pediatric …, 2002 - Elsevier
Purpose: The authors investigated the effect of gestational age on lung development and
maturation after in utero tracheal occlusion (TO) in a rabbit model of congenital …

Pulmonary hypoplasia and congenital diaphragmatic hernia: advances in the pathogenetics and regulation of lung development

MR Chinoy - Journal of Surgical Research, 2002 - Elsevier
Developmental defects remain a leading cause of infant mortality throughout the world. A
recent review suggested that approximately 46% of the defects associated with infant death …

Congenital diaphragmatic hernia: state of the art in translating experimental research to the bedside

L Antounians, RL Figueira, L Sbragia… - European Journal of …, 2019 - thieme-connect.com
Congenital diaphragmatic hernia (CDH) is a devastating disease that still carries a high
mortality and morbidity rate. Poor outcomes for fetuses and infants with CDH are mainly …

New insights into congenital diaphragmatic hernia–a surgeon's introduction to CDH animal models

PPL Chiu - Frontiers in pediatrics, 2014 - frontiersin.org
In recent decades, new research into the developmental defects and pathophysiological
basis of congenital diaphragmatic hernia (CDH) has revealed opportunities for the …

Vitamin A deficiency (VAD), teratogenic, and surgical models of congenital diaphragmatic hernia (CDH)

DE Kling, JJ Schnitzer - … Journal of Medical Genetics Part C …, 2007 - Wiley Online Library
Congenital diaphragmatic hernia (CDH) is a congenital malformation that occurs with a
frequency of 0.08 to 0.45 per 1,000 births. Children with CDH are born with the abdominal …