Telomerase is the enzyme responsible for maintenance of the length of telomeres by
addition of guanine-rich repetitive sequences. Telomerase activity is exhibited in gametes …

Telomerase is an enzyme that maintains the length of the telomere. The telomere length
specifies the number of divisions a cell can undergo before it finally dies (ie the proliferative …

The protein catalytic subunit of telomerase (TERT) is a reverse transcriptase (RT) that
utilizes an internal RNA molecule as a template for the extension of chromosomal DNA …

The life cycle of telomerase involves dynamic and complex interactions between proteins
within multiple macromolecular networks. Elucidation of these associations is a key to …

На концах хромосом эукариот расположены ДНК-белковые структуры–теломеры. Они,
защищая линейные концы хромосом эукариот от деградации и слияния, поддерживают …

На концах хромосом находятся специальные структуры теломеры, от длины которых
зависит пролиферативный потенциал клетки, или число делений, которые клетка …

Telomerase, a ribonucleoprotein, is responsible for the maintenance of eukaryotic genome
integrity by replicating the ends of chromosomes. The core enzyme comprises the …

Telomerase is a key participant of telomere length maintenance system in majority of
eukaryotes. It synthesizes telomere repeats at 3′-end of telomere DNA according to its own …

Telomerase is a cellular reverse transcriptase that elongates the single-stranded
chromosome ends and oligonucleotides in vivo and in vitro. In Saccharomyces cerevisiae …

Through elegant studies in fungal cells and complex organisms, we propose a unifying
paradigm for the rapid evolution of telomere binding proteins (TBPs) that associate with …