Mitochondria are critical in numerous cellular processes, including energy generation.
Bacterial pathogens target host cell mitochondria through various mechanisms to disturb the …

Mycobacterial diseases are a major public health challenge. Their causative agents include,
in order of impact, members of the Mycobacterium tuberculosis complex (causing …

In humans, mitochondria play key roles in the regulation of cellular functions, such as the
regulation of the innate immune response and are targets of several pathogenic viruses and …

The initial infection by the obligate intracellular bacillus Mycobacterium leprae evolves to
leprosy in a small subset of the infected individuals. Transmission is believed to occur …

Background High-resolution metabolomics (HRM) is an innovative tool to study challenging
infectious diseases like leprosy, where the pathogen cannot be grown with standard …

Background In recent years, the mitochondria/immune system interaction has been
proposed, so that variants of mitochondrial genome and levels of heteroplasmy might …

Prototheca bovis, a highly contagious pathogen, causes bovine mastitis, resulting in
premature culling of affected cows and severe economic losses. Infection with P. bovis …

Peripheral neuropathy is the main cause of physical disability in leprosy patients.
Importantly, the extension and pattern of peripheral damage has been linked to how the host …

Leprosy is a chronic infectious disease caused by Mycobacterium leprae infection in
Schwann cells. Axonopathy is considered a hallmark of leprosy neuropathy and is …

Leprosy, or Hansen's Disease, is a chronic infectious disease caused by Mycobacterium
leprae that affects millions of people worldwide. Despite persistent efforts to combat it …