Bispecific T cell engagers: an emerging therapy for management of hematologic malignancies

Z Tian, M Liu, Y Zhang, X Wang - Journal of hematology & oncology, 2021 - Springer
Harnessing the power of immune cells, especially T cells, to enhance anti-tumor activities
has become a promising strategy in clinical management of hematologic malignancies. The …

Diagnosis and treatment of primary myelodysplastic syndromes in adults: recommendations from the European LeukemiaNet

L Malcovati, E Hellström-Lindberg… - Blood, The Journal …, 2013 - ashpublications.org
Within the myelodysplastic syndrome (MDS) work package of the European LeukemiaNet,
an Expert Panel was selected according to the framework elements of the National Institutes …

Revised international prognostic scoring system for myelodysplastic syndromes

PL Greenberg, H Tuechler, J Schanz… - Blood, The Journal …, 2012 - ashpublications.org
Abstract The International Prognostic Scoring Sytem (IPSS) is an important standard for
ssessing prognosis of primary untreated adult patients with myelodysplastic syndromes …

Myelodysplastic syndromes

A Tefferi, JW Vardiman - New England Journal of Medicine, 2009 - Mass Medical Soc
This review gives an account of the clinical and hematologic features of the myelodysplastic
syndromes. It supplies the latest classification of these disorders, discusses the cytogenetic …

Myelodysplastic syndromes

L Adès, R Itzykson, P Fenaux - The Lancet, 2014 - thelancet.com
Myelodysplastic syndromes are clonal marrow stem-cell disorders, characterised by
ineffective haemopoiesis leading to blood cytopenias, and by progression to acute myeloid …

New insights into the prognostic impact of the karyotype in MDS and correlation with subtypes: evidence from a core dataset of 2124 patients

D Haase, U Germing, J Schanz… - Blood, The Journal …, 2007 - ashpublications.org
We have generated a large, unique database that includes morphologic, clinical,
cytogenetic, and follow-up data from 2124 patients with myelodysplastic syndromes (MDSs) …

Definitions and standards in the diagnosis and treatment of the myelodysplastic syndromes: Consensus statements and report from a working conference

P Valent, HP Horny, JM Bennett, C Fonatsch… - Leukemia research, 2007 - Elsevier
The classification, scoring systems, and response criteria for myelodysplastic syndromes
(MDS) have recently been updated and have become widely accepted. In addition, several …

[HTML][HTML] Myelodysplastic syndromes: moving towards personalized management

E Hellström-Lindberg, M Tobiasson, P Greenberg - Haematologica, 2020 - ncbi.nlm.nih.gov
The myelodysplastic syndromes (MDS) share their origin in the hematopoietic stem cell but
have otherwise very heterogeneous biological and genetic characteristics. Clinical features …

TET2 mutation is an independent favorable prognostic factor in myelodysplastic syndromes (MDSs)

O Kosmider, V Gelsi-Boyer, M Cheok… - Blood, The Journal …, 2009 - ashpublications.org
Oncogenic pathways underlying in the development of myelodysplastic syndromes (MDS)
remain poorly characterized, but mutations of the ten-eleven translocation 2 (TET2) gene are …

Cytogenetic features in myelodysplastic syndromes

D Haase - Annals of hematology, 2008 - Springer
Myelodysplastic syndromes (MDS) comprise a group of bone marrow diseases
characterized by profound heterogeneity in morphologic presentation, clinical course, and …