How microbes affect depression: underlying mechanisms via the Gut–brain axis and the modulating role of probiotics

K Suda, K Matsuda - International journal of molecular sciences, 2022 - mdpi.com
Accumulating evidence suggests that the gut microbiome influences the brain functions and
psychological state of its host via the gut–brain axis, and gut dysbiosis has been linked to …

[HTML][HTML] Gut microbiota composition reflects disease severity and dysfunctional immune responses in patients with COVID-19

YK Yeoh, T Zuo, GCY Lui, F Zhang, Q Liu, AYL Li… - Gut, 2021 - gut.bmj.com
Objective Although COVID-19 is primarily a respiratory illness, there is mounting evidence
suggesting that the GI tract is involved in this disease. We investigated whether the gut …

Depression and antidepressant effects of ketamine and its metabolites: The pivotal role of gut microbiota

H Hua, C Huang, H Liu, X Xu, X Xu, Z Wu, C Liu… - …, 2022 - Elsevier
The discovery of the robust antidepressant actions of ketamine is regarded as one of the
greatest advancements in depression treatment in the past 60 years. Recent findings have …

Noninvasive, microbiome-based diagnosis of inflammatory bowel disease

J Zheng, Q Sun, M Zhang, C Liu, Q Su, L Zhang, Z Xu… - Nature Medicine, 2024 - nature.com
Despite recent progress in our understanding of the association between the gut
microbiome and inflammatory bowel disease (IBD), the role of microbiome biomarkers in …

Lactobacillus johnsonii alleviates colitis by TLR1/2-STAT3 mediated CD206+ macrophagesIL-10 activation

DJC Jia, QW Wang, YY Hu, JM He, QW Ge, YD Qi… - Gut …, 2022 - Taylor & Francis
Imbalance of gut microbiota homeostasis is related to the occurrence of ulcerative colitis
(UC), and probiotics are thought to modulate immune microenvironment and repair barrier …

Sophora japonica flowers and their main phytochemical, rutin, regulate chemically induced murine colitis in association with targeting the NF-κB signaling pathway …

Y Liu, W Huang, S Ji, J Wang, J Luo, B Lu - Food Chemistry, 2022 - Elsevier
Sophora japonica flower, rich in rutin, is a homology of medicine and food that can be used
as an anti-inflammatory agent. Its effects and mechanisms against intestinal inflammation …

Prebiotics and postbiotics synergistic delivery microcapsules from microfluidics for treating colitis

K Yang, X Wang, R Huang, H Wang, P Lan… - Advanced …, 2022 - Wiley Online Library
Manipulation of gut microbiota by bacterial metabolites has shown protective effects against
colitis; while the efficacy is strictly limited by the poor oral delivery efficiency and single drug …

Lifestyle patterns influence the composition of the gut microbiome in a healthy Chinese population

Y Ren, J Wu, Y Wang, L Zhang, J Ren, Z Zhang… - Scientific Reports, 2023 - nature.com
High-throughput sequencing allows for the comprehensive analysis of the human intestinal
microbiota. However, extensive association analyses between the microbiome and lifestyle …

[HTML][HTML] Synthetic bacterial therapies for intestinal diseases based on quorum-sensing circuits

Z Dang, M Gao, L Wang, J Wu, Y Guo, Z Zhu… - Biotechnology …, 2023 - Elsevier
Bacterial therapy has become a key strategy against intestinal infectious diseases in recent
years. Moreover, regulating the gut microbiota through traditional fecal microbiota …

Crohn's disease recurrence updates: first surgery vs. surgical relapse patients display different profiles of ileal microbiota and systemic microbial-associated …

E Russo, L Cinci, L Di Gloria, S Baldi… - Frontiers in …, 2022 - frontiersin.org
Background and aims Crohn's disease (CD) pathogenesis is still unclear. Remodeling in
mucosal microbiota and systemic immunoregulation may represent an important component …