The T‐cell response is central in the adaptive immune‐mediated elimination of pathogen‐
infected and/or cancer cells. This activated T‐cell response can inflict an overwhelming …

Resolution of infections depends on the host's ability to mount a protective immune
response. However, an exacerbated response to infections may result in deleterious lesions …

Neutrophils contribute to pathogen clearance by producing neutrophil extracellular traps
(NETs), which are genomic DNA-based net-like structures that capture bacteria and fungi …

Viral replication and microbial translocation from the gut to the blood during HIV infection
lead to hyperimmune activation, which contributes to the decline in CD4+ T cell numbers …

Natural killer (NK) cells are an important component of the innate immune response against
viral infections. NK cell-mediated cytolytic activity is defective in HIV-infected individuals with …

Background. Kaposi sarcoma-associated herpesvirus (KSHV) is the causal agent for Kaposi
sarcoma (KS) and multicentric Castleman disease (MCD) in human immunodeficiency virus …

Background Cytokines play an important role in controlling the homeostasis of the immune
system and infection with Human Immunodeficiency virus (HIV) leads to deregulated …

Murine models indicate that interleukin-10 (IL-10) can suppress viral clearance, and
interventional blockade of IL-10 activity has been proposed to enhance immunity in chronic …

Interleukin-10 (IL-10) is an immunosuppressive cytokine that signals through STAT3 to
regulate T follicular helper (Tfh) cell differentiation and germinal center formation. In SIV …

The life cycle of human immunodeficiency virus type 1 (HIV-1) is intricately related to the
activation state of the host cells supporting viral replication. Although cellular activation is …