Aims This meta-analysis aims to quantify the association of reduced coronary flow with all-
cause mortality and major adverse cardiovascular events (MACE) across a broad range of …

Angina with nonobstructive coronary arteries (ANOCA) is increasingly recognized and may
affect nearly one-half of patients undergoing invasive coronary angiography for suspected …

Abstract Aim The “2023 AHA/ACC/ACCP/ASPC/NLA/PCNA Guideline for the Management
of Patients With Chronic Coronary Disease” provides an update to and consolidates new …

Cochrane, Maria Crespo Leiro, Anne Dipchand, Brian Feingold, Kathleen Grady, Edward
Horn, Maryl Johnson, Donna Mancini, Sean Pinney, Heather Ross, Kari Wujcik, Andreas …

Background: After heart transplantation, endomyocardial biopsy (EMBx) is used to monitor
for acute rejection (AR). Unfortunately, EMBx is invasive, and its conventional histological …

Background: Approximately one-half of patients undergoing diagnostic coronary
angiography for angina have no significant coronary stenosis, in whom coronary functional …

Traditionally, invasive coronary physiological assessment has focused on the epicardial
coronary artery. More recently, appreciation of the importance of the coronary …

Cardiac allograft vasculopathy (CAV) is a pathologic immune-mediated remodelling of the
vasculature in transplanted hearts and, by impairing perfusion, is the major cause of late …

Background—The principle of continuous thermodilution can be used to calculate absolute
coronary blood flow and microvascular resistance (R). The aim of the study is to explore the …

By 1980, it was thought that we already knew most of the major mechanisms regulating
vascular tone. However, after the somewhat serendipity discovery that endothelium is …