Background Klebsiella pneumoniae is the most common pathogen causing neonatal
infections, leading to high mortality worldwide. Along with increasing antimicrobial use in …

India is one of the largest consumers and producers of antibiotics and a hot spot for the
emergence and proliferation of antimicrobial resistance genes (ARGs). Indian hospital …

Infections caused by multi-drug resistant Klebsiella pneumoniae are a leading cause of
mortality and morbidity among hospitalized patients. In neonatal intensive care units (NICU) …

The prevalence of Carbapenem-resistant Klebsiella pneumoniae (CRKP) is currently
increasing worldwide, prompting WHO to classify it as an urgent public health threat. CRKP …

Objectives Alternation of the colistin resistance–regulating two-component regulatory system
(crrAB) is a colistin-resistance mechanism in Klebsiella pneumoniae (K. pneumoniae), but …

Background Intensive care units are units where healthcare-associated infections (HAIs) are
common and antimicrobial resistance rates are increasing. Microbial contamination in …

Purpose Infections induced by multidrug-resistant (MDR) pathogens are one of the most
common and serious complications in extracorporeal membrane oxygenation (ECMO) …

Klebsiella pneumoniae is an opportunistic pathogen involved in both hospital-and
community-acquired infections. K. pneumoniae is associated with various infections …

Purpose Colistin's FDA weight-based dosing (WBD) and frequency are both expressed in a
broad range. Therefore, a simplified fixed-dose regimen (SFDR) of intravenous colistin …

Genes conferring antibiotic resistance phenotype, particularly to last resort antibiotics, pose
a significant concern globally. Wastewater treatment plant (WWTP) effluent substantially …