Type IV secretion systems (T4SSs) are versatile multiprotein nanomachines spanning the
entire cell envelope in Gram‐negative and Gram‐positive bacteria. They play important …

Bacterial conjugation is one of the main mechanisms for horizontal gene transfer. It
constitutes a key element in the dissemination of antibiotic resistance and virulence genes to …

Bacteria with two cell membranes (diderms) have evolved complex systems for protein
secretion. These systems were extensively studied in some model bacteria, but the …

Eukaryotic microalgae hold great promise for the bioproduction of fuels and higher value
chemicals. However, compared with model genetic organisms such as Escherichia coli and …

Bacterial type IV secretion systems translocate virulence factors into eukaryotic cells,,
distribute genetic material between bacteria and have shown potential as a tool for the …

HUH endonucleases are numerous and widespread in all three domains of life. The major
function of these enzymes is processing a range of mobile genetic elements by catalysing …

Bartonella spp. are facultative intracellular pathogens that employ a unique stealth infection
strategy comprising immune evasion and modulation, intimate interaction with nucleated …

New discoveries in metagenomics and clinical research have highlighted the importance of
the gut microbiota for human health through the regulation of the host immune response and …

Genetic exchange by conjugation is responsible for the spread of resistance, virulence, and
social traits among prokaryotes. Recent works unraveled the functioning of the underlying …

Conjugation of DNA through a type IV secretion system (T4SS) drives horizontal gene
transfer. Yet little is known on the diversity of these nanomachines. We previously found that …