It is an emerging research area to integrate scaffolding materials in microfluidic devices for 3D cell culture (organs-on-a-chip). The technology of organs-on-a-chip holds the potential to …
The basement membrane (BM) of the blood-brain barrier (BBB), a thin extracellular matrix (ECM) sheet underneath the brain microvascular endothelial cells (BMECs), plays crucial …
E Tanzli, A Ehrmann - Applied Sciences, 2021 - mdpi.com
In biotechnology, the field of cell cultivation is highly relevant. Cultivated cells can be used, for example, for the development of biopharmaceuticals and in tissue engineering …
JY Lee, EH Jang, JH Kim, SH Park, Y Kang… - Journal of Controlled …, 2021 - Elsevier
Various perivascular drug delivery techniques have been demonstrated for localized post- treatment of intimal hyperplasia: a vascular inflammatory response caused by endothelial …
S Eom, SM Park, H Hong, J Kwon, SR Oh… - … Applied Materials & …, 2020 - ACS Publications
Electrospinning has shown great potential in tissue engineering and regenerative medicine due to a high surface-area-to-volume ratio and an extracellular matrix-mimicking structure of …
3D cell models have made strides in the past decades in response to failures of 2D cultures to translate targets during the drug discovery process. Here, we report on a novel multiwell …
An extracellular matrix (ECM) membrane made up of ECM hydrogels has great potentials to develop a physiologically relevant organ-on-a-chip because of its biochemical and …
J Li, K Pan, H Tian, L Yin - Macromolecular Materials and …, 2020 - Wiley Online Library
Hydrogels are soft materials with 3D cross‐linked networks of polymer chains that can absorb and hold large amounts of water. Hydrogels have attracted great attention of both …
M Zakharova, MP Tibbe, LS Koch… - Advanced Materials …, 2021 - Wiley Online Library
Traditional Transwell inserts with track‐etched 10 μm thick polymer membranes have been intensively used for studying cellular barriers. However, their thickness hampers direct cell …