[HTML][HTML] Dengue overview: An updated systemic review
Dengue is caused by the dengue virus (DENVs) infection and clinical manifestations include
dengue fever (DF), dengue hemorrhagic fever (DHF), or dengue shock syndrome (DSS) …
dengue fever (DF), dengue hemorrhagic fever (DHF), or dengue shock syndrome (DSS) …
Drug repositioning: new approaches and future prospects for life-debilitating diseases and the COVID-19 pandemic outbreak
Traditionally, drug discovery utilises a de novo design approach, which requires high cost
and many years of drug development before it reaches the market. Novel drug development …
and many years of drug development before it reaches the market. Novel drug development …
Disturbed lipid and amino acid metabolisms in COVID-19 patients
M Masoodi, M Peschka, S Schmiedel… - Journal of molecular …, 2022 - Springer
Abstract The Coronavirus disease 2019 (COVID-19) pandemic is overwhelming the
healthcare systems. Identification of systemic reactions underlying COVID-19 will lead to …
healthcare systems. Identification of systemic reactions underlying COVID-19 will lead to …
A medicinal chemistry perspective of drug repositioning: Recent advances and challenges in drug discovery
T Pillaiyar, S Meenakshisundaram, M Manickam… - European journal of …, 2020 - Elsevier
Drug repurposing is a strategy consisting of finding new indications for already known
marketed drugs used in various clinical settings or highly characterized compounds despite …
marketed drugs used in various clinical settings or highly characterized compounds despite …
Multi-platform omics analysis reveals molecular signature for COVID-19 pathogenesis, prognosis and drug target discovery
Y Li, G Hou, H Zhou, Y Wang, HM Tun, A Zhu… - Signal transduction and …, 2021 - nature.com
Disease progression prediction and therapeutic drug target discovery for Coronavirus
disease 2019 (COVID-19) are particularly important, as there is still no effective strategy for …
disease 2019 (COVID-19) are particularly important, as there is still no effective strategy for …
Multi-omics and artificial intelligence-guided drug repositioning: prospects, challenges, and lessons learned from COVID-19
Y Cong, T Endo - OMICS: A Journal of Integrative Biology, 2022 - liebertpub.com
Drug repurposing is of interest for therapeutics innovation in many human diseases
including coronavirus disease 2019 (COVID-19). Methodological innovations in drug …
including coronavirus disease 2019 (COVID-19). Methodological innovations in drug …
Dengue virus non-structural protein 5 as a versatile, multi-functional effector in host–pathogen interactions
P Bhatnagar, GP Sreekanth… - Frontiers in Cellular …, 2021 - frontiersin.org
Dengue is emerging as one of the most prevalent mosquito-borne viral diseases of humans.
The 11kb RNA genome of the dengue virus encodes three structural proteins (envelope, pre …
The 11kb RNA genome of the dengue virus encodes three structural proteins (envelope, pre …
DrugRepV: a compendium of repurposed drugs and chemicals targeting epidemic and pandemic viruses
Viruses are responsible for causing various epidemics and pandemics with a high mortality
rate eg ongoing SARS-CoronaVirus-2 crisis. The discovery of novel antivirals remains a …
rate eg ongoing SARS-CoronaVirus-2 crisis. The discovery of novel antivirals remains a …
A systems biology approach to better understand human tick-borne diseases
Tick-borne diseases (TBDs) are a growing global health concern. Despite extensive studies,
ill-defined tick-associated pathologies remain with unknown aetiologies. Human …
ill-defined tick-associated pathologies remain with unknown aetiologies. Human …
Drug repositioning suggests a role for the heat shock protein 90 inhibitor geldanamycin in treating COVID-19 infection
Drug repositioning offers an unmatched opportunity to offer novel therapeutics to treat SARS
family of coronaviruses (SARS-FCoVs); an issue that became extremely urgent with the …
family of coronaviruses (SARS-FCoVs); an issue that became extremely urgent with the …