Best practice in the management of behavioural and psychological symptoms of dementia

OP Tible, F Riese, E Savaskan… - Therapeutic advances …, 2017 - journals.sagepub.com
Behavioural and psychological symptoms of dementia (BPSD) occur in most patients with
dementia. They cause great suffering in patients and caregivers, sometimes more so than …

Thalamic pathology and memory loss in early Alzheimer's disease: moving the focus from the medial temporal lobe to Papez circuit

JP Aggleton, A Pralus, AJD Nelson, M Hornberger - Brain, 2016 - academic.oup.com
It is widely assumed that incipient protein pathology in the medial temporal lobe instigates
the loss of episodic memory in Alzheimer's disease, one of the earliest cognitive deficits in …

Apathy associated with neurocognitive disorders: recent progress and future directions

KL Lanctôt, L Agüera-Ortiz, H Brodaty, PT Francis… - Alzheimer's & …, 2017 - Elsevier
Introduction Apathy is common in neurocognitive disorders (NCDs) such as Alzheimer's
disease and mild cognitive impairment. Although the definition of apathy is inconsistent in …

The neurobiology of apathy in depression and neurocognitive impairment in older adults: a review of epidemiological, clinical, neuropsychological and biological …

DC Steffens, M Fahed, KJ Manning, L Wang - Translational psychiatry, 2022 - nature.com
Apathy is a common condition that involves diminished initiative, diminished interest and
diminished emotional expression or responsiveness. It is highly prevalent in the context of a …

Multimodal data analysis of Alzheimer's disease based on clustering evolutionary random forest

X Bi, X Hu, H Wu, Y Wang - IEEE Journal of Biomedical and …, 2020 - ieeexplore.ieee.org
Alzheimer's disease (AD) has become a severe medical challenge. Advances in
technologies produced high-dimensional data of different modalities including functional …

Spatial patterns of white matter hyperintensities: a systematic review

J Botz, V Lohner, MD Schirmer - Frontiers in aging neuroscience, 2023 - frontiersin.org
Background White matter hyperintensities are an important marker of cerebral small vessel
disease. This disease burden is commonly described as hyperintense areas in the cerebral …

Inhibition processes are dissociable and lateralized in human prefrontal cortex

L Cipolotti, B Spanò, C Healy, C Tudor-Sfetea, E Chan… - Neuropsychologia, 2016 - Elsevier
The prefrontal cortex (PFC) is known to make fundamental contributions to executive
functions. However, the precise nature of these contributions is incompletely understood. We …

Structural connectivity subserving verbal fluency revealed by lesion-behavior mapping in stroke patients

M Li, Y Zhang, L Song, R Huang, J Ding, Y Fang, Y Xu… - Neuropsychologia, 2017 - Elsevier
Tests of verbal fluency have been widely used to assess the cognitive functioning of
persons, and are typically classified into two categories (semantic and phonological …

Association of infarct topography and outcome after endovascular thrombectomy in patients with acute ischemic stroke

RW Regenhardt, AK Bonkhoff, M Bretzner… - Neurology, 2022 - AAN Enterprises
Background and Objectives The care of patients with large vessel occlusion (LVO) stroke
has been revolutionized by endovascular thrombectomy (EVT). While EVT has a large effect …

Apathy and risk of probable incident dementia among community-dwelling older adults

MA Bock, A Bahorik, WD Brenowitz, K Yaffe - Neurology, 2020 - AAN Enterprises
Objective To evaluate the association between baseline apathy and probable incident
dementia in a population-based sample of community-dwelling older adults. Methods We …