Cerebral blood flow (CBF) is an important physiologic parameter that is vital for proper
cerebral function and recovery. Current widely accepted methods of measuring CBF are …

In the search of animal stroke models providing translational advantages for biomedical
research, pigs are large mammals with interesting brain characteristics and wide social …

Rapid detection of ischemic conditions at the bedside can improve treatment of acute brain
injury. In this observational study of 11 critically ill brain-injured adults, we employed a …

The purpose of this study was to assess the accuracy of absolute cerebral blood flow (CBF)
measurements obtained by dynamic contrast-enhanced (DCE) near-infrared spectroscopy …

We investigate a scheme for noninvasive continuous monitoring of absolute cerebral blood
flow (CBF) in adult human patients based on a combination of time-resolved dynamic …

The critical closing pressure (CrCP) of the cerebral circulation depends on both tissue
intracranial pressure and vasomotor tone. CrCP defines the arterial blood pressure (ABP) at …

Diffuse correlation spectroscopy (DCS) is a promising technique for brain monitoring as it
can provide a continuous signal that is directly related to cerebral blood flow (CBF); …

Diffuse correlation spectroscopy (DCS) is a non-invasive optical technique capable of
monitoring tissue perfusion. The normalized temporal intensity autocorrelation function …

The blood-brain barrier (BBB) is integral to maintaining a suitable microenvironment for
neurons to function properly. Despite its importance, there are no bedside methods of …

Near-infrared spectroscopy is a noninvasive optical method used primarily to monitor tissue
oxygenation due to the absorption properties of hemoglobin. Accurate estimation of …