Obesity is a complex, chronic disease and global public health challenge. Characterized by
excessive fat accumulation in the body, obesity sharply increases the risk of several …

The ever-increasing prevalence of noncommunicable diseases (NCDs) represents a major
public health burden worldwide. The most common form of NCD is metabolic diseases …

Protein posttranslational modifications (PTMs) refer to the breaking or generation of covalent
bonds on the backbones or amino acid side chains of proteins and expand the diversity of …

Abstracts Bone mainly functions as a supportive framework for the whole body and is the
major regulator of calcium homeostasis and hematopoietic function. Recently, an increasing …

Extracellular vesicles (EVs) are implicated in the crosstalk between adipocytes and other
metabolic organs, and an altered biological cargo has been observed in EVs from human …

Abstract Fibro/Adipogenic Progenitors (FAPs) are muscle-interstitial progenitors mediating
pro-myogenic signals that are critical for muscle homeostasis and regeneration. In …

Reduction and oxidation reactions are essential for biochemical processes. They are part of
metabolic pathways and signal transduction. Reactive oxygen species (ROS) as second …

The exponential increase of patients with diabetes mellitus urges for novel therapeutic
strategies to reduce the socioeconomic burden of this disease. The loss or dysfunction of …

Metabolic diseases including type 2 diabetes mellitus (T2DM), non-alcoholic fatty liver
disease (NAFLD), and metabolic syndrome (MetS) are alarming health burdens around the …

Diabetic nephropathy (DN), a common complication of diabetes mellitus, is the main cause
of end-stage nephropathy, and thus developing novel strategies for reversing DN remains …