International union of basic and clinical pharmacology. xciv. adhesion g protein–coupled receptors

J Hamann, G Aust, D Araç, FB Engel, C Formstone… - Pharmacological …, 2015 - ASPET
The Adhesion family forms a large branch of the pharmacologically important superfamily of
G protein–coupled receptors (GPCRs). As Adhesion GPCRs increasingly receive attention …

The role of GPCRs in bone diseases and dysfunctions

J Luo, P Sun, S Siwko, M Liu, J Xiao - Bone research, 2019 - nature.com
The superfamily of G protein-coupled receptors (GPCRs) contains immense structural and
functional diversity and mediates a myriad of biological processes upon activation by …

[图书][B] The ancient origins of consciousness: How the brain created experience

TE Feinberg, JM Mallatt - 2016 - books.google.com
How consciousness appeared much earlier in evolutionary history than is commonly
assumed, and why all vertebrates and perhaps even some invertebrates are conscious …

Molecular evolution of peptidergic signaling systems in bilaterians

O Mirabeau, JS Joly - … of the national academy of sciences, 2013 - National Acad Sciences
Peptide hormones and their receptors are widespread in metazoans, but the knowledge we
have of their evolutionary relationships remains unclear. Recently, accumulating genome …

The Origin of GPCRs: Identification of Mammalian like Rhodopsin, Adhesion, Glutamate and Frizzled GPCRs in Fungi

A Krishnan, MS Almén, R Fredriksson, HB Schiöth - PloS one, 2012 - journals.plos.org
G protein-coupled receptors (GPCRs) in humans are classified into the five main families
named Glutamate, Rhodopsin, Adhesion, Frizzled and Secretin according to the GRAFS …

Evolution, expression and functional analysis of CXCR3 in neuronal and cardiovascular diseases: a narrative review

D Satarkar, C Patra - Frontiers in Cell and Developmental Biology, 2022 - frontiersin.org
Chemokines form a sophisticated communication network wherein they maneuver the
spatiotemporal migration of immune cells across a system. These chemical messengers are …

Adhesion-GPCRs: emerging roles for novel receptors

S Yona, HH Lin, WO Siu, S Gordon, M Stacey - Trends in biochemical …, 2008 - cell.com
The G protein-coupled receptor (GPCR) family comprises the largest class of cell surface
receptors found in metazoan proteomes. Within the novel GPCR subfamily of adhesion …

Independent HHsearch, Needleman–Wunsch-based, and motif analyses reveal the overall hierarchy for most of the G protein-coupled receptor families

KJV Nordström, M Sällman Almén… - Molecular biology …, 2011 - academic.oup.com
Several families of G protein-coupled receptors (GPCRs) show no significant sequence
similarities to each other, and it has been debated which of them share a common origin. We …

Vomeronasal receptors in vertebrates and the evolution of pheromone detection

L Silva, A Antunes - Annual review of animal biosciences, 2017 - annualreviews.org
Pheromones were identified as chemical signals used for intraspecific communication in
insects (eg, sexual attraction) in the 1950s. However, only almost 40 years later the …

Evolution of genetic networks underlying the emergence of thymopoiesis in vertebrates

B Bajoghli, N Aghaallaei, I Hess, I Rode, N Netuschil… - Cell, 2009 - cell.com
About 500 million years ago, a new type of adaptive immune defense emerged in basal
jawed vertebrates, accompanied by morphological innovations, including the thymus. Did …