Bidirectional communication between the peripheral nervous system (PNS) and the immune
system is a crucial part of an effective but balanced mammalian response to invading …

Crosstalk between the gut microbiota and the host has attracted considerable attention
owing to its involvement in diverse diseases. Chronic kidney disease (CKD) is commonly …

Catecholamines stimulate epithelial proliferation, but the role of sympathetic nerve signaling
in pancreatic ductal adenocarcinoma (PDAC) is poorly understood. Catecholamines …

Catecholamines released by sympathetic nerves can activate adrenergic receptors present
on nearly every cell type, including myeloid-derived suppressor cells (MDSCs). Using in …

The nervous system and immune system have broad and overlapping distributions in the
body, and interactions of these ubiquitous systems are central to the field of …

Cancer-associated fibroblasts (CAF) and nerves, components of the tumor
microenvironment, have each been shown to directly promote gastrointestinal cancers …

Traumatic spinal cord injury (SCI) has widespread physiological effects beyond the
disruption of sensory and motor function, notably the loss of normal autonomic and …

It is from the discovery of leptin and the central nervous system as a regulator of bone
remodeling that the presence of autonomic nerves within the skeleton transitioned from a …

The sympathetic nervous system integrates the functions of multiple organ systems by
regulating their autonomic physiological activities. The immune system is regulated both …

Leptin is an adipocyte-derived hormone not only with an important role in the central control
of energy metabolism, but also with many pleiotropic effects in different physiological …