Nitric oxide (NO) is a neurotransmitter that mediates the activation and inhibition of
inflammatory cascades. Even though physiological NO is required for defense against …

Abstract Purpose of Review To evaluate and report current evidence regarding the
management of bowel dysfunction in spinal cord injury. There is a paucity of high-quality …

Poly (ADP-ribose) polymerase 1 (PARP-1) is a nuclear enzyme that is involved in
physiological processes as DNA repair, genomic stability, and apoptosis. Moreover …

The enhanced production of nitric oxide (NO) via inducible nitric oxide synthase (iNOS) has
been implicated in the pathogenesis of neuronal apoptosis after acute traumatic spinal cord …

As one of trials on neuroprotection after spinal cord injury, we used pregabalin. After spinal
cord injury (SCI) in rats using contusion model, we observed the effect of pregabalin …

This special report traces the path of spinal cord injury (SCI) from ancient times through the
present and provides an optimistic overview of promising clinical trials and avenues of basic …

Transplantation of bone marrow derived mesenchymal stromal cells (MSC) or olfactory
ensheathing cells (OEC) have demonstrated beneficial effects after spinal cord injury (SCI) …

Mitochondrial dysfunction is a direct target of hypoxic/ischemic stress in astrocytes, which
results in the increased production of reactive oxygen species (ROS). Previous reports …

It is well established that L-NAME, a generic NOS inhibitor, stimulates neurogenesis in the
dentate gyrus of the adult rat and corticosterone reduces it. These experiments explore the …

Immunization with neurally derived peptides (INDP) boosts the action of an autoreactive
immune response that has been shown to induce neuroprotection in several …